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Protocatechualdehyde Rescues Oxygen-Glucose Deprivation/Reoxygenation-Induced Endothelial Cells Injury by Inducing Autophagy and Inhibiting Apoptosis via Regulation of SIRT1

Background: Oxidative stress-induced endothelial cell death, such as apoptosis and autophagy, plays a critical role in ischemia-reperfusion injury. Protocatechualdehyde (PCA) is a major bioactive component of the traditional Chinese medicine Salvia miltiorrhiza Bunge (Lamiaceae), and it has been pro...

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Detalles Bibliográficos
Autores principales:	Cao, Shidong, Chen, Senmiao, Qiao, Xilin, Guo, Yan, Liu, Fang, Ding, Zhishan, Jin, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008765/ https://www.ncbi.nlm.nih.gov/pubmed/35431914 http://dx.doi.org/10.3389/fphar.2022.846513

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