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Multivariate association between single-nucleotide polymorphisms in Alzgene linkage regions and structural changes in the brain: discovery, refinement and validation

Using publicly-available data from the Alzheimer’s Disease Neuroimaging Initiative, we investigate the joint association between single-nucleotide polymorphisms (SNPs) in previously established linkage regions for Alzheimer’s disease (AD) and rates of decline in brain structure. In an initial, disco...

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Detalles Bibliográficos
Autores principales: Szefer, Elena, Lu, Donghuan, Nathoo, Farouk, Beg, Mirza Faisal, Graham, Jinko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008768/
https://www.ncbi.nlm.nih.gov/pubmed/29091582
http://dx.doi.org/10.1515/sagmb-2016-0077