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Severe Acute Respiratory Syndrome Type 2‐Causing Coronavirus: Variants and Preventive Strategies

COVID‐19 vaccines have constituted a substantial scientific leap in countering severe acute respiratory syndrome type 2‐causing coronavirus (SARS‐CoV‐2), and worldwide implementation of vaccination programs has significantly contributed to the global pandemic effort by saving many lives. However, th...

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Autores principales: Aydogdu, Mehmet Onur, Rohn, Jennifer L., Jafari, Nazila V., Brako, Francis, Homer‐Vanniasinkam, Shervanthi, Edirisinghe, Mohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008798/
https://www.ncbi.nlm.nih.gov/pubmed/35037418
http://dx.doi.org/10.1002/advs.202104495
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author Aydogdu, Mehmet Onur
Rohn, Jennifer L.
Jafari, Nazila V.
Brako, Francis
Homer‐Vanniasinkam, Shervanthi
Edirisinghe, Mohan
author_facet Aydogdu, Mehmet Onur
Rohn, Jennifer L.
Jafari, Nazila V.
Brako, Francis
Homer‐Vanniasinkam, Shervanthi
Edirisinghe, Mohan
author_sort Aydogdu, Mehmet Onur
collection PubMed
description COVID‐19 vaccines have constituted a substantial scientific leap in countering severe acute respiratory syndrome type 2‐causing coronavirus (SARS‐CoV‐2), and worldwide implementation of vaccination programs has significantly contributed to the global pandemic effort by saving many lives. However, the continuous evolution of the SARS‐CoV‐2 viral genome has resulted in different variants with a diverse range of mutations, some with enhanced virulence compared with previous lineages. Such variants are still a great concern as they have the potential to reduce vaccine efficacy and increase the viral transmission rate. This review summarizes the significant variants of SARS‐CoV‐2 encountered to date (December 2021) and discusses a spectrum of possible preventive strategies, with an emphasis on physical and materials science.
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spelling pubmed-90087982022-04-15 Severe Acute Respiratory Syndrome Type 2‐Causing Coronavirus: Variants and Preventive Strategies Aydogdu, Mehmet Onur Rohn, Jennifer L. Jafari, Nazila V. Brako, Francis Homer‐Vanniasinkam, Shervanthi Edirisinghe, Mohan Adv Sci (Weinh) Reviews COVID‐19 vaccines have constituted a substantial scientific leap in countering severe acute respiratory syndrome type 2‐causing coronavirus (SARS‐CoV‐2), and worldwide implementation of vaccination programs has significantly contributed to the global pandemic effort by saving many lives. However, the continuous evolution of the SARS‐CoV‐2 viral genome has resulted in different variants with a diverse range of mutations, some with enhanced virulence compared with previous lineages. Such variants are still a great concern as they have the potential to reduce vaccine efficacy and increase the viral transmission rate. This review summarizes the significant variants of SARS‐CoV‐2 encountered to date (December 2021) and discusses a spectrum of possible preventive strategies, with an emphasis on physical and materials science. John Wiley and Sons Inc. 2022-01-17 /pmc/articles/PMC9008798/ /pubmed/35037418 http://dx.doi.org/10.1002/advs.202104495 Text en © 2022 The Authors. Advanced Science published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Aydogdu, Mehmet Onur
Rohn, Jennifer L.
Jafari, Nazila V.
Brako, Francis
Homer‐Vanniasinkam, Shervanthi
Edirisinghe, Mohan
Severe Acute Respiratory Syndrome Type 2‐Causing Coronavirus: Variants and Preventive Strategies
title Severe Acute Respiratory Syndrome Type 2‐Causing Coronavirus: Variants and Preventive Strategies
title_full Severe Acute Respiratory Syndrome Type 2‐Causing Coronavirus: Variants and Preventive Strategies
title_fullStr Severe Acute Respiratory Syndrome Type 2‐Causing Coronavirus: Variants and Preventive Strategies
title_full_unstemmed Severe Acute Respiratory Syndrome Type 2‐Causing Coronavirus: Variants and Preventive Strategies
title_short Severe Acute Respiratory Syndrome Type 2‐Causing Coronavirus: Variants and Preventive Strategies
title_sort severe acute respiratory syndrome type 2‐causing coronavirus: variants and preventive strategies
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008798/
https://www.ncbi.nlm.nih.gov/pubmed/35037418
http://dx.doi.org/10.1002/advs.202104495
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