Facile and wide-range size tuning of conjugated polymer nanoparticles for biomedical applications as a fluorescent probe

Conjugated polymer nanoparticles (Pdots) are expected to be novel bioimaging and sensing probes. However, the size tuning required to control biological interactions has not been well established. Herein, we achieved a size-tunable synthesis of Pdots ranging from 30 to 200 nm by controlling the hydr...

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Detalles Bibliográficos
Autores principales: Nakamura, Noriko, Tanaka, Nobuaki, Ohta, Seiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008803/
https://www.ncbi.nlm.nih.gov/pubmed/35432941
http://dx.doi.org/10.1039/d1ra09101h
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author Nakamura, Noriko
Tanaka, Nobuaki
Ohta, Seiichi
author_facet Nakamura, Noriko
Tanaka, Nobuaki
Ohta, Seiichi
author_sort Nakamura, Noriko
collection PubMed
description Conjugated polymer nanoparticles (Pdots) are expected to be novel bioimaging and sensing probes. However, the size tuning required to control biological interactions has not been well established. Herein, we achieved a size-tunable synthesis of Pdots ranging from 30 to 200 nm by controlling the hydrolysis rate of the stabilising agent and evaluated their cellular imaging properties.
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spelling pubmed-90088032022-04-14 Facile and wide-range size tuning of conjugated polymer nanoparticles for biomedical applications as a fluorescent probe Nakamura, Noriko Tanaka, Nobuaki Ohta, Seiichi RSC Adv Chemistry Conjugated polymer nanoparticles (Pdots) are expected to be novel bioimaging and sensing probes. However, the size tuning required to control biological interactions has not been well established. Herein, we achieved a size-tunable synthesis of Pdots ranging from 30 to 200 nm by controlling the hydrolysis rate of the stabilising agent and evaluated their cellular imaging properties. The Royal Society of Chemistry 2022-04-14 /pmc/articles/PMC9008803/ /pubmed/35432941 http://dx.doi.org/10.1039/d1ra09101h Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Nakamura, Noriko
Tanaka, Nobuaki
Ohta, Seiichi
Facile and wide-range size tuning of conjugated polymer nanoparticles for biomedical applications as a fluorescent probe
title Facile and wide-range size tuning of conjugated polymer nanoparticles for biomedical applications as a fluorescent probe
title_full Facile and wide-range size tuning of conjugated polymer nanoparticles for biomedical applications as a fluorescent probe
title_fullStr Facile and wide-range size tuning of conjugated polymer nanoparticles for biomedical applications as a fluorescent probe
title_full_unstemmed Facile and wide-range size tuning of conjugated polymer nanoparticles for biomedical applications as a fluorescent probe
title_short Facile and wide-range size tuning of conjugated polymer nanoparticles for biomedical applications as a fluorescent probe
title_sort facile and wide-range size tuning of conjugated polymer nanoparticles for biomedical applications as a fluorescent probe
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008803/
https://www.ncbi.nlm.nih.gov/pubmed/35432941
http://dx.doi.org/10.1039/d1ra09101h
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AT tanakanobuaki facileandwiderangesizetuningofconjugatedpolymernanoparticlesforbiomedicalapplicationsasafluorescentprobe
AT ohtaseiichi facileandwiderangesizetuningofconjugatedpolymernanoparticlesforbiomedicalapplicationsasafluorescentprobe

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