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Pembrolizumab Combined With Neoadjuvant Chemotherapy Versus Neoadjuvant Chemoradiotherapy Followed by Surgery for Locally Advanced Oesophageal Squamous Cell Carcinoma: Protocol for a Multicentre, Prospective, Randomized-Controlled, Phase III Clinical Study (Keystone-002)
BACKGROUND: To compare the efficacy and safety of pembrolizumab combined with neoadjuvant chemotherapy (neoCT) versus neoadjuvant chemoradiotherapy (neoCRT) followed by surgery for locally advanced resectable oesophageal squamous cell carcinoma (ESCC). METHODS: This study is a multicentre, prospecti...
Autores principales: | Shang, Xiaobin, Zhang, Wencheng, Zhao, Gang, Liang, Fei, Zhang, Chen, Yue, Jie, Duan, Xiaofeng, Ma, Zhao, Chen, Chuangui, Pang, Qingsong, Zhang, Weihong, Liu, Liang, Ren, Xiubao, Meng, Bin, Zhang, Peng, Ma, Yegang, Zhang, Lin, Li, Hecheng, Kang, Xiaozheng, Li, Yin, Jiang, Hongjing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008846/ https://www.ncbi.nlm.nih.gov/pubmed/35433421 http://dx.doi.org/10.3389/fonc.2022.831345 |
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