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Association of a novel 27-gene immuno-oncology assay with efficacy of immune checkpoint inhibitors in advanced non-small cell lung cancer
BACKGROUND: Immune checkpoint inhibitor (ICI) therapies represent a major advance in treating a variety of advanced-stage malignancies. Nevertheless, only a subset of patients benefit, even when selected based on approved biomarkers such as PD-L1 and tumor mutational burden. New biomarkers are neede...
Autores principales: | Ranganath, Harsha, Jain, Amit L., Smith, Justin R., Ryder, Julie, Chaudry, Amina, Miller, Emily, Hare, Felicia, Valasareddy, Poojitha, Seitz, Robert S., Hout, David R., Varga, Matthew G., Schweitzer, Brock L., Nielsen, Tyler J., Mullins, Janice, Ross, Douglas T., Gandara, David R., Vidal, Gregory A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008990/ https://www.ncbi.nlm.nih.gov/pubmed/35421940 http://dx.doi.org/10.1186/s12885-022-09470-y |
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