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Quantitative restoration of immune defense in old animals determined by naive antigen‐specific CD8 T‐cell numbers

Older humans and animals often exhibit reduced immune responses to infection and vaccination, and this often directly correlates to the numbers and frequency of naive T (Tn) cells. We found such a correlation between reduced numbers of blood CD8+ Tn cells and severe clinical outcomes of West Nile vi...

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Detalles Bibliográficos
Autores principales:	Uhrlaub, Jennifer L., Jergović, Mladen, Bradshaw, Christine M., Sonar, Sandip, Coplen, Christopher P., Dudakov, Jarrod, Murray, Kristy O., Lanteri, Marion C., Busch, Michael P., van den Brink, Marcel R. M., Nikolich‐Žugich, Janko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009107/ https://www.ncbi.nlm.nih.gov/pubmed/35289071 http://dx.doi.org/10.1111/acel.13582

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