Cargando…

Remodeling Tumor‐Associated Neutrophils to Enhance Dendritic Cell‐Based HCC Neoantigen Nano‐Vaccine Efficiency

Hepatocellular carcinoma (HCC) commonly emerges in an immunologically “cold” state, thereafter protects it away from cytolytic attack by tumor‐infiltrating lymphocytes, resulting in poor response to immunotherapy. Herein, an acidic/photo‐sensitive dendritic cell (DCs)‐based neoantigen nano‐vaccine h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yunhao, Zhao, Qingfu, Zhao, Binyu, Zheng, Youshi, Zhuang, Qiuyu, Liao, Naishun, Wang, Peiyuan, Cai, Zhixiong, Zhang, Da, Zeng, Yongyi, Liu, Xiaolong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009112/ https://www.ncbi.nlm.nih.gov/pubmed/35142445 http://dx.doi.org/10.1002/advs.202105631

Ejemplares similares

Navoximod modulates local HSV-1 replication to reshape tumor immune microenvironment for enhanced immunotherapy via an injectable hydrogel
por: Zhuang, Qiuyu, et al.
Publicado: (2023)

Cytosolic Delivery of Thiolated Neoantigen Nano‐Vaccine Combined with Immune Checkpoint Blockade to Boost Anti‐Cancer T Cell Immunity
por: Zhang, Da, et al.
Publicado: (2021)

Personalized neoantigen-based immunotherapy for advanced collecting duct carcinoma: case report
por: Zeng, Yongyi, et al.
Publicado: (2020)

Adipose tissue-derived stem cells ameliorate hyperglycemia, insulin resistance and liver fibrosis in the type 2 diabetic rats
por: Liao, Naishun, et al.
Publicado: (2017)

Inflammatory Micro-environment Contributes to Stemness Properties and Metastatic Potential of HCC via the NF-κB/miR-497/SALL4 Axis
por: Zhao, Bixing, et al.
Publicado: (2019)

Antioxidant preconditioning improves therapeutic outcomes of adipose tissue-derived mesenchymal stem cells through enhancing intrahepatic engraftment efficiency in a mouse liver fibrosis model
por: Liao, Naishun, et al.
Publicado: (2020)

Antioxidants inhibit cell senescence and preserve stemness of adipose tissue-derived stem cells by reducing ROS generation during long-term in vitro expansion
por: Liao, Naishun, et al.
Publicado: (2019)

Caveolin-mediated cytosolic delivery of spike nanoparticle enhances antitumor immunity of neoantigen vaccine for hepatocellular carcinoma
por: Lin, Zhiwen, et al.
Publicado: (2023)

Natural killer cells modified with a Gpc3 aptamer enhance adoptive immunotherapy for hepatocellular carcinoma
por: Zheng, Youshi, et al.
Publicado: (2023)

Profiling of hepatocellular carcinoma neoantigens reveals immune microenvironment and clonal evolution related patterns
por: Li, Zhenli, et al.
Publicado: (2021)

Personalized neoantigen vaccine prevents postoperative recurrence in hepatocellular carcinoma patients with vascular invasion
por: Cai, Zhixiong, et al.
Publicado: (2021)

α-Methylacyl-CoA racemase (AMACR) serves as a prognostic biomarker for the early recurrence/metastasis of HCC
por: Xu, Bo, et al.
Publicado: (2014)

Unique true predicted neoantigens (TPNAs) correlates with anti-tumor immune control in HCC patients
por: Petrizzo, Annacarmen, et al.
Publicado: (2018)

Personalized neoantigen pulsed dendritic cell vaccine for advanced lung cancer
por: Ding, Zhenyu, et al.
Publicado: (2021)

Research progress of neoantigen-based dendritic cell vaccines in pancreatic cancer
por: Zhang, Xin, et al.
Publicado: (2023)

Personalized neoantigen-pulsed dendritic cell vaccines show superior immunogenicity to neoantigen-adjuvant vaccines in mouse tumor models
por: Zhang, Rui, et al.
Publicado: (2019)

Decoupled neoantigen cross-presentation by dendritic cells limits anti-tumor immunity against tumors with heterogeneous neoantigen expression
por: Nguyen, Kim Bich, et al.
Publicado: (2023)

Advanced HCC Patient Benefit From Neoantigen Reactive T Cells Based Immunotherapy: A Case Report
por: Liu, Chenxi, et al.
Publicado: (2021)

Spleen‐targeted neoantigen DNA vaccine for personalized immunotherapy of hepatocellular carcinoma
por: Wu, Ming, et al.
Publicado: (2023)

Targeting neoantigens for cancer immunotherapy
por: Zhao, Xuan, et al.
Publicado: (2021)

Harnessing neutrophil plasticity for HCC immunotherapy
por: Ramon-Gil, Erik, et al.
Publicado: (2023)

High Somatic Mutation and Neoantigen Burden Do Not Correlate with Decreased Progression-Free Survival in HCC Patients not Undergoing Immunotherapy
por: Mauriello, Angela, et al.
Publicado: (2019)

NeoFox: annotating neoantigen candidates with neoantigen features
por: Lang, Franziska, et al.
Publicado: (2021)

3D-cultured adipose tissue-derived stem cells inhibit liver cancer cell migration and invasion through suppressing epithelial-mesenchymal transition
por: Xie, Haihua, et al.
Publicado: (2018)

High-affinity neoantigens correlate with better prognosis and trigger potent antihepatocellular carcinoma (HCC) activity by activating CD39(+)CD8(+) T cells
por: Liu, Ting, et al.
Publicado: (2021)

Lymphoma neoantigens
por: Elias, Joshua E.
Publicado: (2018)

Neoantigen‐based cancer vaccination using chimeric RNA‐loaded dendritic cell‐derived extracellular vesicles
por: Xiong, Xiao, et al.
Publicado: (2022)

Poly (dopamine) coated superparamagnetic iron oxide nanocluster for noninvasive labeling, tracking, and targeted delivery of adipose tissue-derived stem cells
por: Liao, Naishun, et al.
Publicado: (2016)

Evaluation and prediction of hepatocellular carcinoma prognosis based on molecular classification
por: Ke, Kun, et al.
Publicado: (2018)

Circulating Neutrophils Predict Poor Survival for HCC and Promote HCC Progression Through p53 and STAT3 Signaling Pathway
por: Wang, Yan, et al.
Publicado: (2020)

Neoantigens: promising targets for cancer therapy
por: Xie, Na, et al.
Publicado: (2023)

LncRNA TIALD contributes to hepatocellular carcinoma metastasis via inducing AURKA lysosomal degradation
por: Wang, Yingchao, et al.
Publicado: (2023)

Hepatobiliary Tumor Organoids Reveal HLA Class I Neoantigen Landscape and Antitumoral Activity of Neoantigen Peptide Enhanced with Immune Checkpoint Inhibitors
por: Wang, Wenwen, et al.
Publicado: (2022)

Leveraging a powerful allogeneic dendritic cell line towards neoantigen-based cancer vaccines
por: Hannani, Dalil, et al.
Publicado: (2023)

Neoantigen landscape in metastatic nasopharyngeal carcinoma
por: Lin, Mei, et al.
Publicado: (2021)

Determinants for Neoantigen Identification
por: Garcia-Garijo, Andrea, et al.
Publicado: (2019)

Neoantigens in Hematologic Malignancies
por: Biernacki, Melinda A., et al.
Publicado: (2020)

An Optogenetic Controllable T Cell System for Hepatocellular Carcinoma Immunotherapy
por: Zhao, Bixing, et al.
Publicado: (2019)

The role of neoantigen in immune checkpoint blockade therapy
por: Yi, Ming, et al.
Publicado: (2018)

An 8-gene predicting survival model of hepatocellular carcinoma (HCC) related to pyroptosis and cuproptosis
por: Wang, Hongjin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_j8a06ff0ftorqfmvfo0rnm3579