Deuterated docosahexaenoic acid protects against oxidative stress and geographic atrophy‐like retinal degeneration in a mouse model with iron overload

Oxidative stress plays a central role in age‐related macular degeneration (AMD). Iron, a potent generator of hydroxyl radicals through the Fenton reaction, has been implicated in AMD. One easily oxidized molecule is docosahexaenoic acid (DHA), the most abundant polyunsaturated fatty acid in photorec...

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Detalles Bibliográficos
Autores principales: Liu, Yingrui, Bell, Brent A., Song, Ying, Zhang, Kevin, Anderson, Brandon, Axelsen, Paul H., Bohannan, Whitney, Agbaga, Martin‐Paul, Park, Hui Gyu, James, Genevieve, Brenna, J. Thomas, Schmidt, Karsten, Dunaief, Joshua L., Shchepinov, Mikhail S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009113/
https://www.ncbi.nlm.nih.gov/pubmed/35257475
http://dx.doi.org/10.1111/acel.13579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009113/
https://www.ncbi.nlm.nih.gov/pubmed/35257475
http://dx.doi.org/10.1111/acel.13579

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