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Acidic nanoparticles protect against α‐synuclein‐induced neurodegeneration through the restoration of lysosomal function

Parkinson's disease (PD) is an age‐related neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra, associated with the accumulation of misfolded α‐synuclein and lysosomal impairment, two events deemed interconnected. Protein aggregation is linked to...

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Detalles Bibliográficos
Autores principales: Arotcarena, Marie‐Laure, Soria, Federico N., Cunha, Anthony, Doudnikoff, Evelyne, Prévot, Geoffrey, Daniel, Jonathan, Blanchard‐Desce, Mireille, Barthélémy, Philippe, Bezard, Erwan, Crauste‐Manciet, Sylvie, Dehay, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009122/
https://www.ncbi.nlm.nih.gov/pubmed/35318803
http://dx.doi.org/10.1111/acel.13584

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