Inhibition of unfolded protein response prevents post‐anesthesia neuronal hyperactivity and synapse loss in aged mice

Delirium is the most common postoperative complication in older patients after prolonged anesthesia and surgery and is associated with accelerated cognitive decline and dementia. The neuronal pathogenesis of postoperative delirium is largely unknown. The unfolded protein response (UPR) is an adaptiv...

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Detalles Bibliográficos
Autores principales: Chen, Kai, Hu, Qiuping, Gupta, Riya, Stephens, Jessie, Xie, Zhongcong, Yang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009124/
https://www.ncbi.nlm.nih.gov/pubmed/35299279
http://dx.doi.org/10.1111/acel.13592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009124/
https://www.ncbi.nlm.nih.gov/pubmed/35299279
http://dx.doi.org/10.1111/acel.13592

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