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Transcription Factor Hematopoietically Expressed Homeobox Protein (Hhex) Negatively Regulates Osteoclast Differentiation by Controlling Cyclin‐Dependent Kinase Inhibitors

We investigated the role of hematopoietically expressed homeobox protein (Hhex) in osteoclast development. Trimethylation of lysine 27 of histone H3 at the cis‐regulatory element of Hhex was maintained and that of lysine 4 was reduced during receptor activator of nuclear factor κB ligand (RANKL)‐ind...

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Detalles Bibliográficos
Autores principales: Watanabe, Hisato, Okada, Hiroyuki, Hirose, Jun, Omata, Yasunori, Matsumoto, Takumi, Matsumoto, Morio, Nakamura, Masaya, Saito, Taku, Miyamoto, Takeshi, Tanaka, Sakae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009129/
https://www.ncbi.nlm.nih.gov/pubmed/35434453
http://dx.doi.org/10.1002/jbm4.10608

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