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Transcription Factor Hematopoietically Expressed Homeobox Protein (Hhex) Negatively Regulates Osteoclast Differentiation by Controlling Cyclin‐Dependent Kinase Inhibitors
We investigated the role of hematopoietically expressed homeobox protein (Hhex) in osteoclast development. Trimethylation of lysine 27 of histone H3 at the cis‐regulatory element of Hhex was maintained and that of lysine 4 was reduced during receptor activator of nuclear factor κB ligand (RANKL)‐ind...
Autores principales: | Watanabe, Hisato, Okada, Hiroyuki, Hirose, Jun, Omata, Yasunori, Matsumoto, Takumi, Matsumoto, Morio, Nakamura, Masaya, Saito, Taku, Miyamoto, Takeshi, Tanaka, Sakae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009129/ https://www.ncbi.nlm.nih.gov/pubmed/35434453 http://dx.doi.org/10.1002/jbm4.10608 |
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