Cargando…
Case Report: Cerebral Venous Sinus Thrombosis in a Young Child With SARS-CoV-2 Infection: The Italian Experience
INTRODUCTION: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pediatric patients is usually characterized by fever, dry cough, and fatigue, or is asymptomatic and rarely presents with pneumonia. On the other hand, cerebral venous sinus thrombosis (CVST) could be a neurologi...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009147/ https://www.ncbi.nlm.nih.gov/pubmed/35432183 http://dx.doi.org/10.3389/fneur.2022.861345 |
_version_ | 1784687213877919744 |
---|---|
author | Silvestri, Paola Clemente, Anna Spalice, Alberto Febbo, Alessandra Matera, Luigi Accardo, Fabiana Barbieri, Maria Antonietta Villani, Alberto Midulla, Fabio |
author_facet | Silvestri, Paola Clemente, Anna Spalice, Alberto Febbo, Alessandra Matera, Luigi Accardo, Fabiana Barbieri, Maria Antonietta Villani, Alberto Midulla, Fabio |
author_sort | Silvestri, Paola |
collection | PubMed |
description | INTRODUCTION: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pediatric patients is usually characterized by fever, dry cough, and fatigue, or is asymptomatic and rarely presents with pneumonia. On the other hand, cerebral venous sinus thrombosis (CVST) could be a neurological sequela of the prothrombotic state triggered by coronavirus disease 2019 (COVID-19) both in adults and children. CASE REPORT: We present a case of a 15-year-old male child who was obese and had mild neurocognitive impairment. He was admitted to the pediatric emergency department and then diagnosed with CVST during SARS-CoV-2 infection. CONCLUSION: During the COVID-19 pandemic, in patients presenting with neurological manifestations of CVST (headache, alteration of consciousness, focal deficit, or signs of endocranial hypertension), it is advisable to look for a current or recent infection of SARS-CoV-2, regardless of the presence of respiratory symptoms. In our patient, ongoing SARS-CoV-2 infection represents the only prothrombotic risk factor underlying the neurological disease. |
format | Online Article Text |
id | pubmed-9009147 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-90091472022-04-15 Case Report: Cerebral Venous Sinus Thrombosis in a Young Child With SARS-CoV-2 Infection: The Italian Experience Silvestri, Paola Clemente, Anna Spalice, Alberto Febbo, Alessandra Matera, Luigi Accardo, Fabiana Barbieri, Maria Antonietta Villani, Alberto Midulla, Fabio Front Neurol Neurology INTRODUCTION: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pediatric patients is usually characterized by fever, dry cough, and fatigue, or is asymptomatic and rarely presents with pneumonia. On the other hand, cerebral venous sinus thrombosis (CVST) could be a neurological sequela of the prothrombotic state triggered by coronavirus disease 2019 (COVID-19) both in adults and children. CASE REPORT: We present a case of a 15-year-old male child who was obese and had mild neurocognitive impairment. He was admitted to the pediatric emergency department and then diagnosed with CVST during SARS-CoV-2 infection. CONCLUSION: During the COVID-19 pandemic, in patients presenting with neurological manifestations of CVST (headache, alteration of consciousness, focal deficit, or signs of endocranial hypertension), it is advisable to look for a current or recent infection of SARS-CoV-2, regardless of the presence of respiratory symptoms. In our patient, ongoing SARS-CoV-2 infection represents the only prothrombotic risk factor underlying the neurological disease. Frontiers Media S.A. 2022-03-31 /pmc/articles/PMC9009147/ /pubmed/35432183 http://dx.doi.org/10.3389/fneur.2022.861345 Text en Copyright © 2022 Silvestri, Clemente, Spalice, Febbo, Matera, Accardo, Barbieri, Villani and Midulla. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neurology Silvestri, Paola Clemente, Anna Spalice, Alberto Febbo, Alessandra Matera, Luigi Accardo, Fabiana Barbieri, Maria Antonietta Villani, Alberto Midulla, Fabio Case Report: Cerebral Venous Sinus Thrombosis in a Young Child With SARS-CoV-2 Infection: The Italian Experience |
title | Case Report: Cerebral Venous Sinus Thrombosis in a Young Child With SARS-CoV-2 Infection: The Italian Experience |
title_full | Case Report: Cerebral Venous Sinus Thrombosis in a Young Child With SARS-CoV-2 Infection: The Italian Experience |
title_fullStr | Case Report: Cerebral Venous Sinus Thrombosis in a Young Child With SARS-CoV-2 Infection: The Italian Experience |
title_full_unstemmed | Case Report: Cerebral Venous Sinus Thrombosis in a Young Child With SARS-CoV-2 Infection: The Italian Experience |
title_short | Case Report: Cerebral Venous Sinus Thrombosis in a Young Child With SARS-CoV-2 Infection: The Italian Experience |
title_sort | case report: cerebral venous sinus thrombosis in a young child with sars-cov-2 infection: the italian experience |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009147/ https://www.ncbi.nlm.nih.gov/pubmed/35432183 http://dx.doi.org/10.3389/fneur.2022.861345 |
work_keys_str_mv | AT silvestripaola casereportcerebralvenoussinusthrombosisinayoungchildwithsarscov2infectiontheitalianexperience AT clementeanna casereportcerebralvenoussinusthrombosisinayoungchildwithsarscov2infectiontheitalianexperience AT spalicealberto casereportcerebralvenoussinusthrombosisinayoungchildwithsarscov2infectiontheitalianexperience AT febboalessandra casereportcerebralvenoussinusthrombosisinayoungchildwithsarscov2infectiontheitalianexperience AT materaluigi casereportcerebralvenoussinusthrombosisinayoungchildwithsarscov2infectiontheitalianexperience AT accardofabiana casereportcerebralvenoussinusthrombosisinayoungchildwithsarscov2infectiontheitalianexperience AT barbierimariaantonietta casereportcerebralvenoussinusthrombosisinayoungchildwithsarscov2infectiontheitalianexperience AT villanialberto casereportcerebralvenoussinusthrombosisinayoungchildwithsarscov2infectiontheitalianexperience AT midullafabio casereportcerebralvenoussinusthrombosisinayoungchildwithsarscov2infectiontheitalianexperience |