Acrolein, an endogenous aldehyde induces synaptic dysfunction in vitro and in vivo: Involvement of RhoA/ROCK2 pathway

Acrolein, an unsaturated aldehyde, is increased in the brain of Alzheimer's disease (AD) patients and identified as a potential inducer of sporadic AD. Synaptic dysfunction, as a typical pathological change occurring in the early stage of AD, is most closely associated with the severity of deme...

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Detalles Bibliográficos
Autores principales: Zhu, Zeyu, Lu, Junfeng, Wang, Shuyi, Peng, Weijia, Yang, Yang, Chen, Chen, Zhou, Xin, Yang, Xifei, Xin, Wenjun, Chen, Xinyi, Pi, Jiakai, Yin, Wei, Yao, Lin, Pi, Rongbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009232/
https://www.ncbi.nlm.nih.gov/pubmed/35315217
http://dx.doi.org/10.1111/acel.13587

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