Generation of Tumor-Specific Cytotoxic T Cells From Blood via In Vitro Expansion Using Autologous Dendritic Cells Pulsed With Neoantigen-Coupled Microbeads

For the past decade, adoptive cell therapy including tumor-infiltrating lymphocytes, genetically modified cytotoxic lymphocytes expressing a chimeric antigen receptor, or a novel T-cell receptor has revolutionized the treatment of many cancers. Progress within exome sequencing and neoantigen predict...

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Detalles Bibliográficos
Autores principales: Kiessling, Adela, Ramanathan, Keerthana, Nilsson, Ola B., Notari, Luigi, Renken, Stefanie, Kiessling, Rolf, Grönlund, Hans, Wickström, Stina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009257/
https://www.ncbi.nlm.nih.gov/pubmed/35433456
http://dx.doi.org/10.3389/fonc.2022.866763

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