Simultaneous Alteration of the Circadian Variation of Memory, Hippocampal Synaptic Plasticity, and Metabolism in a Triple Transgenic Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is characterized by progressive memory deficits accompanied by synaptic and metabolic deficits, namely of mitochondrial function. AD patients also display a disrupted circadian pattern. Thus, we now compared memory performance, synaptic plasticity, and mitochondria function...

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Detalles Bibliográficos
Autores principales: Carvalho da Silva, António M., Lemos, Cristina, Silva, Henrique B., Ferreira, Ildete L., Tomé, Angelo R., Rego, A. Cristina, Cunha, Rodrigo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009366/
https://www.ncbi.nlm.nih.gov/pubmed/35431906
http://dx.doi.org/10.3389/fnagi.2022.835885

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