Cargando…

Effects of ApoE4 and ApoE2 genotypes on subcortical magnetic susceptibility and microstructure in 27,535 participants from the UK Biobank()

Disrupted iron homeostasis is associated with several neurodegenerative diseases, including Alzheimer’s disease (AD), and may be partially modulated by genetic risk factors. Here we evaluated whether subcortical iron deposition is associated with ApoE genotype, which substantially affects risk for l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nir, Talia M., Zhu, Alyssa H., Gari, Iyad Ba, Dixon, Daniel, Islam, Tasfiya, Villalon-Reina, Julio E., Medland, Sarah E., Thompson, Paul M., Jahanshad, Neda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009383/ https://www.ncbi.nlm.nih.gov/pubmed/34890142

Ejemplares similares

Age and sex effects on advanced white matter microstructure measures in 15,628 older adults: A UK biobank study
por: Lawrence, Katherine E., et al.
Publicado: (2021)

Genetic map of regional sulcal morphology in the human brain from UK biobank data
por: Sun, Benjamin B., et al.
Publicado: (2022)

Multisite test–retest reliability and compatibility of brain metrics derived from FreeSurfer versions 7.1, 6.0, and 5.3
por: Haddad, Elizabeth, et al.
Publicado: (2022)

ApoE e4e4 Genotype and Mortality With COVID-19 in UK Biobank
por: Kuo, Chia-Ling, et al.
Publicado: (2020)

ApoE and apoE receptors in brain lipid metabolism and AD
por: Bu, Guojun
Publicado: (2012)

ApoE e2 and aging-related outcomes in 379,000 UK Biobank participants
por: Kuo, Chia-Ling, et al.
Publicado: (2020)

Vascular hypothesis of Alzheimer’s disease: role of apoE and apoE receptors
por: Bu, Guojun, et al.
Publicado: (2013)

Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice
por: Hu, Jin, et al.
Publicado: (2015)

Lipoprotein glomerulopathy induced by ApoE Kyoto mutation in ApoE-deficient mice
por: Wu, Hongyan, et al.
Publicado: (2021)

Brain ApoA-I, ApoJ and ApoE Immunodetection in Cerebral Amyloid Angiopathy
por: Camacho, Jessica, et al.
Publicado: (2019)

Commentary: Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk
por: Dzianok, Patrycja, et al.
Publicado: (2020)

ApoE polymorphisms in narcolepsy
por: Gencik, Martin, et al.
Publicado: (2001)

Potential role of ATM in hepatocyte endocytosis of ApoE-deficient, ApoB48-containing lipoprotein in ApoE-deficient mice
por: WU, JIANHUA, et al.
Publicado: (2014)

Mercury Ion Binding to Apolipoprotein E Variants ApoE2, ApoE3, and ApoE4: Similar Binding Affinities but Different Structure Induction Effects
por: Berntsson, Elina, et al.
Publicado: (2022)

Comment on “ApoE e4e4 Genotype and Mortality With COVID-19 in UK Biobank” by Kuo et al
por: Nikogosov, Dimitri A, et al.
Publicado: (2020)

APOE e4 Genotype Predicts Severe COVID-19 in the UK Biobank Community Cohort
por: Kuo, Chia-Ling, et al.
Publicado: (2020)

Increased ApoE Expression in Follicular Fluid and the ApoE Genotype Are Associated With Endometriosis in Chinese Women
por: Liu, Ya-Jing, et al.
Publicado: (2021)

Response to Comment on “ApoE e4e4 Genotype and Mortality With COVID-19 in UK Biobank” by Kuo et al.
por: Kuo, Chia-Ling, et al.
Publicado: (2020)

Apolipoprotein E (ApoE) ε4 Genotype (ApoE rs429358—ApoE rs7412 Polymorphisms) Is Not Associated with Long COVID Symptoms in Previously Hospitalized COVID-19 Survivors
por: Fernández-de-las-Peñas, César, et al.
Publicado: (2023)

Sex Differences in Presynaptic Density and Neurogenesis in Middle-Aged ApoE4 and ApoE Knockout Mice
por: Rijpma, A., et al.
Publicado: (2013)

A Case of Lipoprotein Glomerulopathy with apoE Chicago and apoE (Glu3Lys) Treated with Fenofibrate
por: Kodera, Hitoshi, et al.
Publicado: (2017)

Harnessing the paradoxical phenotypes of APOE ɛ2 and APOE ɛ4 to identify genetic modifiers in Alzheimer's disease
por: Kim, Young Won, et al.
Publicado: (2020)

The Role of ApoE Serum Levels and ApoE Gene Polymorphisms in Patients with Laryngeal Squamous Cell Carcinoma
por: Liutkeviciene, Rasa, et al.
Publicado: (2022)

Opposing effects of apoE2 and apoE4 on microglial activation and lipid metabolism in response to demyelination
por: Wang, Na, et al.
Publicado: (2022)

Commentary: APOE e4 Genotype Predicts Severe COVID-19 in the UK Biobank Community Cohort
por: Kasparian, Kyle, et al.
Publicado: (2020)

ApoE4 Induces Synaptic and ERG Impairments in the Retina of Young Targeted Replacement ApoE4 Mice
por: Antes, Ran, et al.
Publicado: (2013)

Effect of apoA-I on cholesterol release and apoE secretion in human mature adipocytes
por: Bencharif, Karima, et al.
Publicado: (2010)

Antibodies against apoB100 peptide 210 inhibit atherosclerosis in apoE(-/-) mice
por: Dunér, Pontus, et al.
Publicado: (2021)

Novel action of apolipoprotein E (ApoE): ApoE isoform specifically inhibits lipid-particle-mediated cholesterol release from neurons
por: Gong, Jian-Sheng, et al.
Publicado: (2007)

The Role of ApoE in HCV Infection and Comorbidity
por: Gong, Yue, et al.
Publicado: (2019)

ApoE4 Astrocytes Secrete Basement Membranes Rich in Fibronectin and Poor in Laminin Compared to ApoE3 Astrocytes
por: Keable, Abby, et al.
Publicado: (2020)

ApoE and ApoE Nascent-Like HDL Particles at Model Cellular Membranes: Effect of Protein Isoform and Membrane Composition
por: Waldie, Sarah, et al.
Publicado: (2021)

Current and Emerging Reconstituted HDL-apoA-I and HDL-apoE Approaches to Treat Atherosclerosis
por: Valanti, Eftaxia-Konstantina, et al.
Publicado: (2018)

Association of APOE With Primary Open-Angle Glaucoma Suggests a Protective Effect for APOE ɛ4
por: Margeta, Milica A., et al.
Publicado: (2020)

ApoE Alzheimer’s Disease Aβ-amyloid plaque morphology varies according to APOE isotype
por: Caesar, Ina, et al.
Publicado: (2023)

Is ApoE ɛ 4 a good biomarker for amyloid pathology in late onset Alzheimer’s disease?
por: Ba, Maowen, et al.
Publicado: (2016)

ApoE3 vs. ApoE4 Astrocytes: A Detailed Analysis Provides New Insights into Differences in Cholesterol Homeostasis
por: Staurenghi, Erica, et al.
Publicado: (2022)

Non-Invasive Intranasal Delivery of pApoE2: Effect of Multiple Dosing on the ApoE2 Expression in Mice Brain
por: Gothwal, Avinash, et al.
Publicado: (2023)

Intranasal Delivery of E-Selectin Reduces Atherosclerosis in ApoE−/− Mice
por: Li, Xinhui, et al.
Publicado: (2011)

Effect of apolipoprotein E (APO E) polymorphism on leptin in Alzheimer's disease
por: Agarwal, Rachna, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_9quj6mfa17ugjmuh8o4a5cav9q