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Preventing Phosphorylation of the GABA(A)R β3 Subunit Compromises the Behavioral Effects of Neuroactive Steroids

Neuroactive steroids (NASs) have potent anxiolytic, anticonvulsant, sedative, and hypnotic actions, that reflect in part their efficacy as GABA(A)R positive allosteric modulators (PAM). In addition to this, NAS exert metabotropic effects on GABAergic inhibition via the activation of membrane progest...

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Detalles Bibliográficos
Autores principales:	Vien, Thuy N., Ackley, Michael A., Doherty, James J., Moss, Stephen J., Davies, Paul A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009507/ https://www.ncbi.nlm.nih.gov/pubmed/35431797 http://dx.doi.org/10.3389/fnmol.2022.817996

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