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Double Lung Transplantation Bridged With Direct Central Ambulatory Veno-Arterial Extracorporeal Membrane Oxygenation in a Pulmonary Hypertension Patient With Extreme Mediastinal Shift

Lung transplantation is increasingly being performed for end-stage lung disease in patients with bronchiectasis and pulmonary hypertension. Outcomes of bilateral lung transplantation (BLT) are better in patients with pulmonary hypertension, whereas single lung transplant remains a controversy in bro...

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Autores principales: Lodhi, Samra Haroon, Nandavaram, Sravanthi, Malyala, Raj, Anstead, Michael, Keshavamurthy, Suresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009749/
https://www.ncbi.nlm.nih.gov/pubmed/35444889
http://dx.doi.org/10.7759/cureus.23070
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author Lodhi, Samra Haroon
Nandavaram, Sravanthi
Malyala, Raj
Anstead, Michael
Keshavamurthy, Suresh
author_facet Lodhi, Samra Haroon
Nandavaram, Sravanthi
Malyala, Raj
Anstead, Michael
Keshavamurthy, Suresh
author_sort Lodhi, Samra Haroon
collection PubMed
description Lung transplantation is increasingly being performed for end-stage lung disease in patients with bronchiectasis and pulmonary hypertension. Outcomes of bilateral lung transplantation (BLT) are better in patients with pulmonary hypertension, whereas single lung transplant remains a controversy in bronchiectasis with fear of infections from the residual diseased lung. However, in patients with adhesions and extreme structural changes due to severe disease, BLT may be considered technically challenging. We describe a case of successful management of a patient with bronchiectasis-induced lung disease causing extreme mediastinal shift with a BLT. The patient was successfully bridged to transplant with central veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for acute decompensated pulmonary hypertension while awaiting transplantation.
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spelling pubmed-90097492022-04-19 Double Lung Transplantation Bridged With Direct Central Ambulatory Veno-Arterial Extracorporeal Membrane Oxygenation in a Pulmonary Hypertension Patient With Extreme Mediastinal Shift Lodhi, Samra Haroon Nandavaram, Sravanthi Malyala, Raj Anstead, Michael Keshavamurthy, Suresh Cureus Internal Medicine Lung transplantation is increasingly being performed for end-stage lung disease in patients with bronchiectasis and pulmonary hypertension. Outcomes of bilateral lung transplantation (BLT) are better in patients with pulmonary hypertension, whereas single lung transplant remains a controversy in bronchiectasis with fear of infections from the residual diseased lung. However, in patients with adhesions and extreme structural changes due to severe disease, BLT may be considered technically challenging. We describe a case of successful management of a patient with bronchiectasis-induced lung disease causing extreme mediastinal shift with a BLT. The patient was successfully bridged to transplant with central veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for acute decompensated pulmonary hypertension while awaiting transplantation. Cureus 2022-03-11 /pmc/articles/PMC9009749/ /pubmed/35444889 http://dx.doi.org/10.7759/cureus.23070 Text en Copyright © 2022, Lodhi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Lodhi, Samra Haroon
Nandavaram, Sravanthi
Malyala, Raj
Anstead, Michael
Keshavamurthy, Suresh
Double Lung Transplantation Bridged With Direct Central Ambulatory Veno-Arterial Extracorporeal Membrane Oxygenation in a Pulmonary Hypertension Patient With Extreme Mediastinal Shift
title Double Lung Transplantation Bridged With Direct Central Ambulatory Veno-Arterial Extracorporeal Membrane Oxygenation in a Pulmonary Hypertension Patient With Extreme Mediastinal Shift
title_full Double Lung Transplantation Bridged With Direct Central Ambulatory Veno-Arterial Extracorporeal Membrane Oxygenation in a Pulmonary Hypertension Patient With Extreme Mediastinal Shift
title_fullStr Double Lung Transplantation Bridged With Direct Central Ambulatory Veno-Arterial Extracorporeal Membrane Oxygenation in a Pulmonary Hypertension Patient With Extreme Mediastinal Shift
title_full_unstemmed Double Lung Transplantation Bridged With Direct Central Ambulatory Veno-Arterial Extracorporeal Membrane Oxygenation in a Pulmonary Hypertension Patient With Extreme Mediastinal Shift
title_short Double Lung Transplantation Bridged With Direct Central Ambulatory Veno-Arterial Extracorporeal Membrane Oxygenation in a Pulmonary Hypertension Patient With Extreme Mediastinal Shift
title_sort double lung transplantation bridged with direct central ambulatory veno-arterial extracorporeal membrane oxygenation in a pulmonary hypertension patient with extreme mediastinal shift
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009749/
https://www.ncbi.nlm.nih.gov/pubmed/35444889
http://dx.doi.org/10.7759/cureus.23070
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