Capsaicin as an amphipathic modulator of Na(V)1.5 mechanosensitivity

SCN5A-encoded Na(V)1.5 is a voltage-gated Na(+) channel that drives the electrical excitability of cardiac myocytes and contributes to slow waves of the human gastrointestinal smooth muscle cells. Na(V)1.5 is mechanosensitive: mechanical force modulates several facets of Na(V)1.5’s voltage-gated fun...

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Detalles Bibliográficos
Autores principales: Cowan, Luke M., Strege, Peter R., Rusinova, Radda, Andersen, Olaf S., Farrugia, Gianrico, Beyder, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009938/
https://www.ncbi.nlm.nih.gov/pubmed/35412435
http://dx.doi.org/10.1080/19336950.2022.2026015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009938/
https://www.ncbi.nlm.nih.gov/pubmed/35412435
http://dx.doi.org/10.1080/19336950.2022.2026015

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