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A European cross-sectional survey to investigate how involved doctors training in clinical pharmacology are in drug concentration monitoring

PURPOSE: Therapeutic drug monitoring (TDM) is widely recognised as a key attribute of clinical pharmacologists; yet, the extent to which physicians undertaking postgraduate training in clinical pharmacology (hereafter trainees) are involved in TDM is poorly characterised. Our own experience suggests...

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Autores principales: Green, Thomas J., Walker, Lauren E., Turner, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009980/
https://www.ncbi.nlm.nih.gov/pubmed/35426080
http://dx.doi.org/10.1007/s00228-022-03316-z
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author Green, Thomas J.
Walker, Lauren E.
Turner, Richard M.
author_facet Green, Thomas J.
Walker, Lauren E.
Turner, Richard M.
author_sort Green, Thomas J.
collection PubMed
description PURPOSE: Therapeutic drug monitoring (TDM) is widely recognised as a key attribute of clinical pharmacologists; yet, the extent to which physicians undertaking postgraduate training in clinical pharmacology (hereafter trainees) are involved in TDM is poorly characterised. Our own experience suggests wide variation in trainee exposure to TDM. METHOD: We performed a Europe-wide cross-sectional internet-based survey of trainees to determine the nature and extent of trainee involvement in TDM. RESULTS: There were 43 responses from eight countries analysed. Of the 21 respondents from the UK, all were also training in general internal medicine (GIM), while all of the respondents who were solely training in clinical pharmacology were from outside the UK. Overall, 86.0% of respondents reported access to drug monitoring for clinical care at their affiliated institution, of which 81.0% were personally involved in TDM in some capacity. On average, trainees reported that drug monitoring was available for 16 of the 33 (48%) of the drug/drug classes surveyed. UK-based respondents were involved in requesting drug-level investigations and interpreting the results for patients under their care in 76.2% and 85.7% of cases, respectively, while non-UK respondents supported other healthcare professionals to interpret results in 45.4% of cases. Trainees felt TDM training was generally either insufficient or very inadequate. CONCLUSION: While access to TDM is relatively available at institutions where trainees are based, the role of trainees is variable and affected by a variety of factors including country and training programme. Universally, trainees feel they need more education in TDM.
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spelling pubmed-90099802022-04-15 A European cross-sectional survey to investigate how involved doctors training in clinical pharmacology are in drug concentration monitoring Green, Thomas J. Walker, Lauren E. Turner, Richard M. Eur J Clin Pharmacol Pharmacokinetics and Disposition PURPOSE: Therapeutic drug monitoring (TDM) is widely recognised as a key attribute of clinical pharmacologists; yet, the extent to which physicians undertaking postgraduate training in clinical pharmacology (hereafter trainees) are involved in TDM is poorly characterised. Our own experience suggests wide variation in trainee exposure to TDM. METHOD: We performed a Europe-wide cross-sectional internet-based survey of trainees to determine the nature and extent of trainee involvement in TDM. RESULTS: There were 43 responses from eight countries analysed. Of the 21 respondents from the UK, all were also training in general internal medicine (GIM), while all of the respondents who were solely training in clinical pharmacology were from outside the UK. Overall, 86.0% of respondents reported access to drug monitoring for clinical care at their affiliated institution, of which 81.0% were personally involved in TDM in some capacity. On average, trainees reported that drug monitoring was available for 16 of the 33 (48%) of the drug/drug classes surveyed. UK-based respondents were involved in requesting drug-level investigations and interpreting the results for patients under their care in 76.2% and 85.7% of cases, respectively, while non-UK respondents supported other healthcare professionals to interpret results in 45.4% of cases. Trainees felt TDM training was generally either insufficient or very inadequate. CONCLUSION: While access to TDM is relatively available at institutions where trainees are based, the role of trainees is variable and affected by a variety of factors including country and training programme. Universally, trainees feel they need more education in TDM. Springer Berlin Heidelberg 2022-04-14 2022 /pmc/articles/PMC9009980/ /pubmed/35426080 http://dx.doi.org/10.1007/s00228-022-03316-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Pharmacokinetics and Disposition
Green, Thomas J.
Walker, Lauren E.
Turner, Richard M.
A European cross-sectional survey to investigate how involved doctors training in clinical pharmacology are in drug concentration monitoring
title A European cross-sectional survey to investigate how involved doctors training in clinical pharmacology are in drug concentration monitoring
title_full A European cross-sectional survey to investigate how involved doctors training in clinical pharmacology are in drug concentration monitoring
title_fullStr A European cross-sectional survey to investigate how involved doctors training in clinical pharmacology are in drug concentration monitoring
title_full_unstemmed A European cross-sectional survey to investigate how involved doctors training in clinical pharmacology are in drug concentration monitoring
title_short A European cross-sectional survey to investigate how involved doctors training in clinical pharmacology are in drug concentration monitoring
title_sort european cross-sectional survey to investigate how involved doctors training in clinical pharmacology are in drug concentration monitoring
topic Pharmacokinetics and Disposition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009980/
https://www.ncbi.nlm.nih.gov/pubmed/35426080
http://dx.doi.org/10.1007/s00228-022-03316-z
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