A Case of Idiopathic Cold Agglutinin Hemolytic Anemia Successfully Treated With Steroids

Cold agglutinin disease (CAD) is a type of hemolytic anemia in which cold agglutinins can cause agglutination of red blood cells in cold parts of the body and hemolytic anemia. Cold agglutinin-mediated hemolytic anemia can occur in the setting of an underlying viral infection, autoimmune disorder, o...

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Autores principales: Haider, Asim, Alavi, Fareeha, Siddiqa, Ayesha, Owais, Muhammad, Khan, Muzammil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009994/
https://www.ncbi.nlm.nih.gov/pubmed/35444893
http://dx.doi.org/10.7759/cureus.23172
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author Haider, Asim
Alavi, Fareeha
Siddiqa, Ayesha
Owais, Muhammad
Khan, Muzammil
author_facet Haider, Asim
Alavi, Fareeha
Siddiqa, Ayesha
Owais, Muhammad
Khan, Muzammil
author_sort Haider, Asim
collection PubMed
description Cold agglutinin disease (CAD) is a type of hemolytic anemia in which cold agglutinins can cause agglutination of red blood cells in cold parts of the body and hemolytic anemia. Cold agglutinin-mediated hemolytic anemia can occur in the setting of an underlying viral infection, autoimmune disorder, or lymphoid malignancy, referred to as a secondary cold agglutinin syndrome, or without one of these underlying disorders, referred to as primary CAD (also known as idiopathic CAD). We present a case of a 71-year-old female with hemolytic anemia due to primary CAD. The secondary causes of CAD, including infections, autoimmune disorders, and malignancy, were ruled out. She was successfully treated with prednisone.
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spelling pubmed-90099942022-04-19 A Case of Idiopathic Cold Agglutinin Hemolytic Anemia Successfully Treated With Steroids Haider, Asim Alavi, Fareeha Siddiqa, Ayesha Owais, Muhammad Khan, Muzammil Cureus Internal Medicine Cold agglutinin disease (CAD) is a type of hemolytic anemia in which cold agglutinins can cause agglutination of red blood cells in cold parts of the body and hemolytic anemia. Cold agglutinin-mediated hemolytic anemia can occur in the setting of an underlying viral infection, autoimmune disorder, or lymphoid malignancy, referred to as a secondary cold agglutinin syndrome, or without one of these underlying disorders, referred to as primary CAD (also known as idiopathic CAD). We present a case of a 71-year-old female with hemolytic anemia due to primary CAD. The secondary causes of CAD, including infections, autoimmune disorders, and malignancy, were ruled out. She was successfully treated with prednisone. Cureus 2022-03-15 /pmc/articles/PMC9009994/ /pubmed/35444893 http://dx.doi.org/10.7759/cureus.23172 Text en Copyright © 2022, Haider et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Haider, Asim
Alavi, Fareeha
Siddiqa, Ayesha
Owais, Muhammad
Khan, Muzammil
A Case of Idiopathic Cold Agglutinin Hemolytic Anemia Successfully Treated With Steroids
title A Case of Idiopathic Cold Agglutinin Hemolytic Anemia Successfully Treated With Steroids
title_full A Case of Idiopathic Cold Agglutinin Hemolytic Anemia Successfully Treated With Steroids
title_fullStr A Case of Idiopathic Cold Agglutinin Hemolytic Anemia Successfully Treated With Steroids
title_full_unstemmed A Case of Idiopathic Cold Agglutinin Hemolytic Anemia Successfully Treated With Steroids
title_short A Case of Idiopathic Cold Agglutinin Hemolytic Anemia Successfully Treated With Steroids
title_sort case of idiopathic cold agglutinin hemolytic anemia successfully treated with steroids
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9009994/
https://www.ncbi.nlm.nih.gov/pubmed/35444893
http://dx.doi.org/10.7759/cureus.23172
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