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Therapeutic Targets for Heart Failure Identified Using Proteomics and Mendelian Randomization
Heart failure (HF) is a highly prevalent disorder for which disease mechanisms are incompletely understood. The discovery of disease-associated proteins with causal genetic evidence provides an opportunity to identify new therapeutic targets. METHODS: We investigated the observational and causal ass...
Autores principales: | Henry, Albert, Gordillo-Marañón, María, Finan, Chris, Schmidt, Amand F., Ferreira, João Pedro, Karra, Ravi, Sundström, Johan, Lind, Lars, Ärnlöv, Johan, Zannad, Faiez, Mälarstig, Anders, Hingorani, Aroon D., Lumbers, R. Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010023/ https://www.ncbi.nlm.nih.gov/pubmed/35300523 http://dx.doi.org/10.1161/CIRCULATIONAHA.121.056663 |
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