Determination of Senegenin and Tenuifolin in Mouse Blood by Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry and Their Pharmacokinetics

An ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for the determination of senegenin and tenuifolin in mouse blood was developed. The pharmacokinetics of senegenin and tenuifolin in mice after intravenous (5 mg/kg) and oral (60 mg/kg) administration were st...

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Detalles Bibliográficos
Autores principales: Shen, Xiuwei, Dai, Xiangyi, He, Yifan, Wen, Congcong, Zhang, Qingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010192/
https://www.ncbi.nlm.nih.gov/pubmed/35432545
http://dx.doi.org/10.1155/2022/3401355

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