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Importance of Gedunin in Antagonizing Rheumatoid Arthritis via Activating the Nrf2/ARE Signaling
OBJECTIVE: This study assessed the anti-arthritic effect and protection of Gedunin (GDN) on joint tissues and revealed the possible mechanism in suppressing rheumatoid arthritis (RA). METHODS: LPS-induced macrophages and TNF-α-stimulated synovial fibroblasts (MH7A) or IL-1β-stimulated primary rheuma...
Autores principales: | Chen, Jian-Yu, Tian, Xiao-Yun, Liu, Wen-Jing, Wu, Bao-Kun, Wu, Yue-Chan, Zhu, Ming-Xing, Jin-Liu, Zhou, Xian, Zheng, Yan-Fang, Ma, Xue-Qin, Huang, Ming-Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010203/ https://www.ncbi.nlm.nih.gov/pubmed/35432723 http://dx.doi.org/10.1155/2022/6277760 |
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