Population pharmacokinetic modeling and simulations of berotralstat for prophylactic treatment of attacks of hereditary angioedema

Hereditary angioedema (HAE) is an autosomal dominant disorder characterized by recurrent episodes of swelling of the skin, larynx, gastrointestinal tract, genitals, and extremities that can be disruptive to patient quality of life. Dysregulation of plasma kallikrein activity leads to increased produ...

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Detalles Bibliográficos
Autores principales: Mathis, Amanda, Sale, Mark, Cornpropst, Melanie, Sheridan, William P., Ma, Shu Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010267/
https://www.ncbi.nlm.nih.gov/pubmed/35212456
http://dx.doi.org/10.1111/cts.13233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010267/
https://www.ncbi.nlm.nih.gov/pubmed/35212456
http://dx.doi.org/10.1111/cts.13233

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