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Leveraging large observational studies to discover genetic determinants of drug concentrations: A proof‐of‐concept study
Large, observational genetic studies are commonly used to identify genetic factors associated with diseases and disease‐related traits. Such cohorts have not been commonly used to identify genetic predictors of drug dosing or concentrations, perhaps because of the heterogeneity in drug dosing and fo...
Autores principales: | Meloche, Maxime, Leclair, Grégoire, Jutras, Martin, Oussaïd, Essaïd, Gaulin, Marie‐Josée, Mongrain, Ian, Busseuil, David, Tardif, Jean‐Claude, Dubé, Marie‐Pierre, de Denus, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010273/ https://www.ncbi.nlm.nih.gov/pubmed/35122397 http://dx.doi.org/10.1111/cts.13230 |
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