Microvascular stabilization via blood-brain barrier regulation prevents seizure activity

Blood-brain barrier (BBB) dysfunction is associated with worse epilepsy outcomes however the underlying molecular mechanisms of BBB dysfunction remain to be elucidated. Tight junction proteins are important regulators of BBB integrity and in particular, the tight junction protein claudin-5 is the mo...

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Detalles Bibliográficos
Autores principales: Greene, Chris, Hanley, Nicole, Reschke, Cristina R., Reddy, Avril, Mäe, Maarja A., Connolly, Ruairi, Behan, Claire, O’Keeffe, Eoin, Bolger, Isobel, Hudson, Natalie, Delaney, Conor, Farrell, Michael A., O’Brien, Donncha F., Cryan, Jane, Brett, Francesca M., Beausang, Alan, Betsholtz, Christer, Henshall, David C., Doherty, Colin P., Campbell, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010415/
https://www.ncbi.nlm.nih.gov/pubmed/35422069
http://dx.doi.org/10.1038/s41467-022-29657-y

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