High-pressure crystallography shows noble gas intervention into protein-lipid interaction and suggests a model for anaesthetic action

In this work we examine how small hydrophobic molecules such as inert gases interact with membrane proteins (MPs) at a molecular level. High pressure atmospheres of argon and krypton were used to produce noble gas derivatives of crystals of three well studied MPs (two different proton pumps and a so...

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Detalles Bibliográficos
Autores principales: Melnikov, Igor, Orekhov, Philipp, Rulev, Maksim, Kovalev, Kirill, Astashkin, Roman, Bratanov, Dmitriy, Ryzhykau, Yury, Balandin, Taras, Bukhdruker, Sergei, Okhrimenko, Ivan, Borshchevskiy, Valentin, Bourenkov, Gleb, Mueller-Dieckmann, Christoph, van der Linden, Peter, Carpentier, Philippe, Leonard, Gordon, Gordeliy, Valentin, Popov, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010423/
https://www.ncbi.nlm.nih.gov/pubmed/35422073
http://dx.doi.org/10.1038/s42003-022-03233-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010423/
https://www.ncbi.nlm.nih.gov/pubmed/35422073
http://dx.doi.org/10.1038/s42003-022-03233-y

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