Cargando…
Lamin A and the LINC complex act as potential tumor suppressors in Ewing Sarcoma
Lamin A, a main constituent of the nuclear lamina, is involved in mechanosignaling and cell migration through dynamic interactions with the LINC complex, formed by the nuclear envelope proteins SUN1, SUN2 and the nesprins. Here, we investigated lamin A role in Ewing Sarcoma (EWS), an aggressive bone...
Autores principales: | Chiarini, Francesca, Paganelli, Francesca, Balestra, Tommaso, Capanni, Cristina, Fazio, Antonietta, Manara, Maria Cristina, Landuzzi, Lorena, Petrini, Stefania, Evangelisti, Camilla, Lollini, Pier-Luigi, Martelli, Alberto M., Lattanzi, Giovanna, Scotlandi, Katia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010457/ https://www.ncbi.nlm.nih.gov/pubmed/35422060 http://dx.doi.org/10.1038/s41419-022-04729-5 |
Ejemplares similares
-
Lamin A and Prelamin A Counteract Migration of Osteosarcoma Cells
por: Evangelisti, Camilla, et al.
Publicado: (2020) -
The Cutting Edge: The Role of mTOR Signaling in Laminopathies
por: Chiarini, Francesca, et al.
Publicado: (2019) -
Patient Derived Xenografts for Genome-Driven Therapy of Osteosarcoma
por: Landuzzi, Lorena, et al.
Publicado: (2021) -
Innovative Breakthroughs for the Treatment of Advanced and Metastatic Synovial Sarcoma
por: Landuzzi, Lorena, et al.
Publicado: (2023) -
Synovial Sarcoma Preclinical Modeling: Integrating Transgenic Mouse Models and Patient-Derived Models for Translational Research
por: Landuzzi, Lorena, et al.
Publicado: (2023)