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Lamin A and the LINC complex act as potential tumor suppressors in Ewing Sarcoma

Lamin A, a main constituent of the nuclear lamina, is involved in mechanosignaling and cell migration through dynamic interactions with the LINC complex, formed by the nuclear envelope proteins SUN1, SUN2 and the nesprins. Here, we investigated lamin A role in Ewing Sarcoma (EWS), an aggressive bone...

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Detalles Bibliográficos
Autores principales:	Chiarini, Francesca, Paganelli, Francesca, Balestra, Tommaso, Capanni, Cristina, Fazio, Antonietta, Manara, Maria Cristina, Landuzzi, Lorena, Petrini, Stefania, Evangelisti, Camilla, Lollini, Pier-Luigi, Martelli, Alberto M., Lattanzi, Giovanna, Scotlandi, Katia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010457/ https://www.ncbi.nlm.nih.gov/pubmed/35422060 http://dx.doi.org/10.1038/s41419-022-04729-5

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