In vivo assessment of OXPHOS capacity using 3 T CrCEST MRI in Friedreich’s ataxia

BACKGROUND: Friedreich’s ataxia (FRDA) is a neurodegenerative disease caused by decreased expression of frataxin, a protein involved in many cellular metabolic processes, including mitochondrial oxidative phosphorylation (OXPHOS). Our objective was to assess skeletal muscle oxidative metabolism in v...

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Detalles Bibliográficos
Autores principales: Schur, Gayatri Maria, Dunn, Julia, Nguyen, Sara, Dedio, Anna, Wade, Kristin, Tamaroff, Jaclyn, Mitta, Nithya, Wilson, Neil, Reddy, Ravinder, Lynch, David R., McCormack, Shana E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010488/
https://www.ncbi.nlm.nih.gov/pubmed/34652504
http://dx.doi.org/10.1007/s00415-021-10821-1

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