Cargando…
Linkage of methionine addiction, histone lysine hypermethylation, and malignancy
Methionine addiction, found in all types of cancer investigated, is because of the overuse of methionine by cancer cells for excess transmethylation reactions. In the present study, we compared the histone H3 lysine-methylation status and degree of malignancy between methionine-addicted cancer cells...
Autores principales: | Yamamoto, Jun, Inubushi, Sachiko, Han, Qinghong, Tashiro, Yoshihiko, Sugisawa, Norihiko, Hamada, Kazuyuki, Aoki, Yusuke, Miyake, Kentaro, Matsuyama, Ryusei, Bouvet, Michael, Clarke, Steven G., Endo, Itaru, Hoffman, Robert M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010622/ https://www.ncbi.nlm.nih.gov/pubmed/35434545 http://dx.doi.org/10.1016/j.isci.2022.104162 |
Ejemplares similares
-
Reversion of methionine addiction of osteosarcoma cells to methionine independence results in loss of malignancy, modulation of the epithelial-mesenchymal phenotype and alteration of histone-H3 lysine-methylation
por: Aoki, Yusuke, et al.
Publicado: (2022) -
Histone H3 lysine-trimethylation markers are decreased by recombinant methioninase and increased by methotrexate at concentrations which inhibit methionine-addicted osteosarcoma cell proliferation
por: Aoki, Yusuke, et al.
Publicado: (2021) -
Ischemia reperfusion-induced metastasis is resistant to PPARγ agonist pioglitazone in a murine model of colon cancer
por: Tashiro, Yoshihiko, et al.
Publicado: (2020) -
Glioblastoma and Methionine Addiction
por: Sowers, Mark L., et al.
Publicado: (2022) -
Old-age-induced obesity reversed by a methionine-deficient diet or oral administration of recombinant methioninase-producing Escherichia coli in C57BL/6 mice
por: Kubota, Yutaro, et al.
Publicado: (2023)