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SP3-Enabled Rapid and High Coverage Chemoproteomic Identification of Cell-State–Dependent Redox-Sensitive Cysteines

Proteinaceous cysteine residues act as privileged sensors of oxidative stress. As reactive oxygen and nitrogen species have been implicated in numerous pathophysiological processes, deciphering which cysteines are sensitive to oxidative modification and the specific nature of these modifications is...

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Detalles Bibliográficos
Autores principales: Desai, Heta S., Yan, Tianyang, Yu, Fengchao, Sun, Alexander W., Villanueva, Miranda, Nesvizhskii, Alexey I., Backus, Keriann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010637/
https://www.ncbi.nlm.nih.gov/pubmed/35219905
http://dx.doi.org/10.1016/j.mcpro.2022.100218

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