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Premise and peril of Wnt signaling activation through GSK-3β inhibition

Wnt signaling pathways have been extensively studied in the context of several diseases, including cancer, coronary artery disease, and age-related disorders. β-Catenin plays a central role in the most studied Wnt pathways, the Wnt/β-catenin signaling pathway, commonly referred to as the canonical W...

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Detalles Bibliográficos
Autores principales: Law, Samuel M., Zheng, Jie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010644/
https://www.ncbi.nlm.nih.gov/pubmed/35434563
http://dx.doi.org/10.1016/j.isci.2022.104159