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Acute Administration of Metformin Protects Against Neuronal Apoptosis Induced by Cerebral Ischemia-Reperfusion Injury via Regulation of the AMPK/CREB/BDNF Pathway

Metformin is a first-line anti-diabetic agent with a powerful hypoglycemic effect. Several studies have reported that metformin can improve the prognosis of stroke patients and that this effect is independent of its hypoglycemic effect; however, the specific mechanism remains unclear. In this resear...

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Detalles Bibliográficos
Autores principales:	Liu, Ke, Li, Lulu, Liu, Zhijun, Li, Gang, Wu, Yanqing, Jiang, Xingjun, Wang, Mengdie, Chang, Yanmin, Jiang, Tingting, Luo, Jianheng, Zhu, Jiahui, Li, Hongge, Wang, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010658/ https://www.ncbi.nlm.nih.gov/pubmed/35431946 http://dx.doi.org/10.3389/fphar.2022.832611

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