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Research Advances on Matrine
Matrine is an alkaloid extracted from traditional Chinese herbs including Sophora flavescentis, Sophora alopecuroides, Sophora root, etc. It has the dual advantages of traditional Chinese herbs and chemotherapy drugs. It exhibits distinct benefits in preventing and improving chronic diseases such as...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010661/ https://www.ncbi.nlm.nih.gov/pubmed/35433636 http://dx.doi.org/10.3389/fchem.2022.867318 |
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author | Sun, Xiao-Ying Jia, Li-Yi Rong, Zheng Zhou, Xin Cao, Lu-Qi Li, Ai-Hong Guo, Meng Jin, Jie Wang, Yin-Di Huang, Ling Li, Yi-Heng He, Zhong-Jing Li, Long Ma, Rui-Kang Lv, Yi-Fan Shao, Ke-Ke Zhang, Juan Cao, Hui-Ling |
author_facet | Sun, Xiao-Ying Jia, Li-Yi Rong, Zheng Zhou, Xin Cao, Lu-Qi Li, Ai-Hong Guo, Meng Jin, Jie Wang, Yin-Di Huang, Ling Li, Yi-Heng He, Zhong-Jing Li, Long Ma, Rui-Kang Lv, Yi-Fan Shao, Ke-Ke Zhang, Juan Cao, Hui-Ling |
author_sort | Sun, Xiao-Ying |
collection | PubMed |
description | Matrine is an alkaloid extracted from traditional Chinese herbs including Sophora flavescentis, Sophora alopecuroides, Sophora root, etc. It has the dual advantages of traditional Chinese herbs and chemotherapy drugs. It exhibits distinct benefits in preventing and improving chronic diseases such as cardiovascular disease and tumors. The review introduced recent research progresses on extraction, synthesis and derivatization of Matrine. The summary focused on the latest research advances of Matrine on anti-atherosclerosis, anti-hypertension, anti-ischemia reperfusion injury, anti-arrhythmia, anti-diabetic cardiovascular complications, anti-tumor, anti-inflammatory, anti-bacterium, anti-virus, which would provide new core structures and new insights for new drug development in related fields. |
format | Online Article Text |
id | pubmed-9010661 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-90106612022-04-16 Research Advances on Matrine Sun, Xiao-Ying Jia, Li-Yi Rong, Zheng Zhou, Xin Cao, Lu-Qi Li, Ai-Hong Guo, Meng Jin, Jie Wang, Yin-Di Huang, Ling Li, Yi-Heng He, Zhong-Jing Li, Long Ma, Rui-Kang Lv, Yi-Fan Shao, Ke-Ke Zhang, Juan Cao, Hui-Ling Front Chem Chemistry Matrine is an alkaloid extracted from traditional Chinese herbs including Sophora flavescentis, Sophora alopecuroides, Sophora root, etc. It has the dual advantages of traditional Chinese herbs and chemotherapy drugs. It exhibits distinct benefits in preventing and improving chronic diseases such as cardiovascular disease and tumors. The review introduced recent research progresses on extraction, synthesis and derivatization of Matrine. The summary focused on the latest research advances of Matrine on anti-atherosclerosis, anti-hypertension, anti-ischemia reperfusion injury, anti-arrhythmia, anti-diabetic cardiovascular complications, anti-tumor, anti-inflammatory, anti-bacterium, anti-virus, which would provide new core structures and new insights for new drug development in related fields. Frontiers Media S.A. 2022-04-01 /pmc/articles/PMC9010661/ /pubmed/35433636 http://dx.doi.org/10.3389/fchem.2022.867318 Text en Copyright © 2022 Sun, Jia, Rong, Zhou, Cao, Li, Guo, Jin, Wang, Huang, Li, He, Li, Ma, Lv, Shao, Zhang and Cao. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Chemistry Sun, Xiao-Ying Jia, Li-Yi Rong, Zheng Zhou, Xin Cao, Lu-Qi Li, Ai-Hong Guo, Meng Jin, Jie Wang, Yin-Di Huang, Ling Li, Yi-Heng He, Zhong-Jing Li, Long Ma, Rui-Kang Lv, Yi-Fan Shao, Ke-Ke Zhang, Juan Cao, Hui-Ling Research Advances on Matrine |
title | Research Advances on Matrine |
title_full | Research Advances on Matrine |
title_fullStr | Research Advances on Matrine |
title_full_unstemmed | Research Advances on Matrine |
title_short | Research Advances on Matrine |
title_sort | research advances on matrine |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010661/ https://www.ncbi.nlm.nih.gov/pubmed/35433636 http://dx.doi.org/10.3389/fchem.2022.867318 |
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