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Research Advances on Matrine

Matrine is an alkaloid extracted from traditional Chinese herbs including Sophora flavescentis, Sophora alopecuroides, Sophora root, etc. It has the dual advantages of traditional Chinese herbs and chemotherapy drugs. It exhibits distinct benefits in preventing and improving chronic diseases such as...

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Autores principales: Sun, Xiao-Ying, Jia, Li-Yi, Rong, Zheng, Zhou, Xin, Cao, Lu-Qi, Li, Ai-Hong, Guo, Meng, Jin, Jie, Wang, Yin-Di, Huang, Ling, Li, Yi-Heng, He, Zhong-Jing, Li, Long, Ma, Rui-Kang, Lv, Yi-Fan, Shao, Ke-Ke, Zhang, Juan, Cao, Hui-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010661/
https://www.ncbi.nlm.nih.gov/pubmed/35433636
http://dx.doi.org/10.3389/fchem.2022.867318
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author Sun, Xiao-Ying
Jia, Li-Yi
Rong, Zheng
Zhou, Xin
Cao, Lu-Qi
Li, Ai-Hong
Guo, Meng
Jin, Jie
Wang, Yin-Di
Huang, Ling
Li, Yi-Heng
He, Zhong-Jing
Li, Long
Ma, Rui-Kang
Lv, Yi-Fan
Shao, Ke-Ke
Zhang, Juan
Cao, Hui-Ling
author_facet Sun, Xiao-Ying
Jia, Li-Yi
Rong, Zheng
Zhou, Xin
Cao, Lu-Qi
Li, Ai-Hong
Guo, Meng
Jin, Jie
Wang, Yin-Di
Huang, Ling
Li, Yi-Heng
He, Zhong-Jing
Li, Long
Ma, Rui-Kang
Lv, Yi-Fan
Shao, Ke-Ke
Zhang, Juan
Cao, Hui-Ling
author_sort Sun, Xiao-Ying
collection PubMed
description Matrine is an alkaloid extracted from traditional Chinese herbs including Sophora flavescentis, Sophora alopecuroides, Sophora root, etc. It has the dual advantages of traditional Chinese herbs and chemotherapy drugs. It exhibits distinct benefits in preventing and improving chronic diseases such as cardiovascular disease and tumors. The review introduced recent research progresses on extraction, synthesis and derivatization of Matrine. The summary focused on the latest research advances of Matrine on anti-atherosclerosis, anti-hypertension, anti-ischemia reperfusion injury, anti-arrhythmia, anti-diabetic cardiovascular complications, anti-tumor, anti-inflammatory, anti-bacterium, anti-virus, which would provide new core structures and new insights for new drug development in related fields.
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spelling pubmed-90106612022-04-16 Research Advances on Matrine Sun, Xiao-Ying Jia, Li-Yi Rong, Zheng Zhou, Xin Cao, Lu-Qi Li, Ai-Hong Guo, Meng Jin, Jie Wang, Yin-Di Huang, Ling Li, Yi-Heng He, Zhong-Jing Li, Long Ma, Rui-Kang Lv, Yi-Fan Shao, Ke-Ke Zhang, Juan Cao, Hui-Ling Front Chem Chemistry Matrine is an alkaloid extracted from traditional Chinese herbs including Sophora flavescentis, Sophora alopecuroides, Sophora root, etc. It has the dual advantages of traditional Chinese herbs and chemotherapy drugs. It exhibits distinct benefits in preventing and improving chronic diseases such as cardiovascular disease and tumors. The review introduced recent research progresses on extraction, synthesis and derivatization of Matrine. The summary focused on the latest research advances of Matrine on anti-atherosclerosis, anti-hypertension, anti-ischemia reperfusion injury, anti-arrhythmia, anti-diabetic cardiovascular complications, anti-tumor, anti-inflammatory, anti-bacterium, anti-virus, which would provide new core structures and new insights for new drug development in related fields. Frontiers Media S.A. 2022-04-01 /pmc/articles/PMC9010661/ /pubmed/35433636 http://dx.doi.org/10.3389/fchem.2022.867318 Text en Copyright © 2022 Sun, Jia, Rong, Zhou, Cao, Li, Guo, Jin, Wang, Huang, Li, He, Li, Ma, Lv, Shao, Zhang and Cao. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Sun, Xiao-Ying
Jia, Li-Yi
Rong, Zheng
Zhou, Xin
Cao, Lu-Qi
Li, Ai-Hong
Guo, Meng
Jin, Jie
Wang, Yin-Di
Huang, Ling
Li, Yi-Heng
He, Zhong-Jing
Li, Long
Ma, Rui-Kang
Lv, Yi-Fan
Shao, Ke-Ke
Zhang, Juan
Cao, Hui-Ling
Research Advances on Matrine
title Research Advances on Matrine
title_full Research Advances on Matrine
title_fullStr Research Advances on Matrine
title_full_unstemmed Research Advances on Matrine
title_short Research Advances on Matrine
title_sort research advances on matrine
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010661/
https://www.ncbi.nlm.nih.gov/pubmed/35433636
http://dx.doi.org/10.3389/fchem.2022.867318
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