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Controlling neural territory patterning from pluripotency using a systems developmental biology approach

Successful manufacture of specialized human cells requires process understanding of directed differentiation. Here, we apply high-dimensional Design of Experiments (HD-DoE) methodology to identify critical process parameters (CPPs) that govern neural territory patterning from pluripotency—the first...

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Detalles Bibliográficos
Autores principales: Sears, Katie E., Gullapalli, Keerthi, Trivedi, Divya, Mihas, Alexander, Bukys, Michael A., Jensen, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010746/
https://www.ncbi.nlm.nih.gov/pubmed/35434550
http://dx.doi.org/10.1016/j.isci.2022.104133