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The HBx protein from hepatitis B virus coordinates a redox-active Fe-S cluster

The viral protein HBx is the key regulatory factor of the hepatitis B virus (HBV) and the main etiology for HBV-associated liver diseases, such as cirrhosis and hepatocellular carcinoma. Historically, HBx has defied biochemical and structural characterization, deterring efforts to understand its mol...

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Detalles Bibliográficos
Autores principales: Ueda, Chie, Langton, Michelle, Chen, Jiahua, Pandelia, Maria-Eirini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010755/
https://www.ncbi.nlm.nih.gov/pubmed/35148994
http://dx.doi.org/10.1016/j.jbc.2022.101698