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The Role of DNA Repair in Immunological Diversity: From Molecular Mechanisms to Clinical Ramifications

An effective humoral immune response necessitates the generation of diverse and high-affinity antibodies to neutralize pathogens and their products. To generate this assorted immune repertoire, DNA damage is introduced at specific regions of the genome. Purposeful genotoxic insults are needed for th...

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Detalles Bibliográficos
Autores principales:	Gullickson, Peter, Xu, Yunwen W., Niedernhofer, Laura J., Thompson, Elizabeth L., Yousefzadeh, Matthew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010869/ https://www.ncbi.nlm.nih.gov/pubmed/35432317 http://dx.doi.org/10.3389/fimmu.2022.834889

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