Cargando…

The Role of DNA Repair in Immunological Diversity: From Molecular Mechanisms to Clinical Ramifications

An effective humoral immune response necessitates the generation of diverse and high-affinity antibodies to neutralize pathogens and their products. To generate this assorted immune repertoire, DNA damage is introduced at specific regions of the genome. Purposeful genotoxic insults are needed for th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gullickson, Peter, Xu, Yunwen W., Niedernhofer, Laura J., Thompson, Elizabeth L., Yousefzadeh, Matthew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010869/ https://www.ncbi.nlm.nih.gov/pubmed/35432317 http://dx.doi.org/10.3389/fimmu.2022.834889

Ejemplares similares

Human NK Cell Diversity in Viral Infection: Ramifications of Ramification
por: Strauss-Albee, Dara M., et al.
Publicado: (2016)

FUCOIDANS ARE NOVEL SENOTHERAPEUTICS THAT ENHANCE SIRT6 AND DNA REPAIR ACTIVITY
por: Zhang, Lei, et al.
Publicado: (2022)

FUCOIDANS ARE NOVEL SENOTHERAPEUTICS THAT ENHANCE SIRT6 AND DNA REPAIR ACTIVITY
por: Zhang, Lei, et al.
Publicado: (2022)

Molecular and immunological mechanisms of clonal evolution in multiple myeloma
por: Forster, Stefan, et al.
Publicado: (2023)

Interaction of Opioids with TLR4—Mechanisms and Ramifications
por: Gabr, Mai Mahmoud, et al.
Publicado: (2021)

Natural killer lytic-associated molecule plays a role in controlling tumor dissemination and metastasis
por: Hoover, Richard G., et al.
Publicado: (2012)

Ramification of indexing of medical journals
por: Chakravarthy, M, et al.
Publicado: (2013)

DNA damage—how and why we age?
por: Yousefzadeh, Matt, et al.
Publicado: (2021)

Total Synthesis of (–)-Anaferine: A Further Ramification in a Diversity-Oriented Approach
por: Bonandi, Elisa, et al.
Publicado: (2020)

Editorial: Unveiling immunological mechanisms of periodontal diseases
por: de Vries, Teun J., et al.
Publicado: (2022)

Editorial: Molecular Dynamics at the Immunological Synapse
por: Alcover, Andrés, et al.
Publicado: (2016)

Distinct Immunological Landscapes Characterize Inherited and Sporadic Mismatch Repair Deficient Endometrial Cancer
por: Ramchander, Neal C., et al.
Publicado: (2020)

Synthetic biology: ethical ramifications 2009
por: Rabinow, Paul, et al.
Publicado: (2009)

Microbiome and Health: Ramifications of Intelligent Deception
por: Stefano, George B., et al.
Publicado: (2018)

Global Ramifications of Dust and Sandstorm Microbiota
por: Behzad, Hayedeh, et al.
Publicado: (2018)

Premenstrual syndrome and its psychiatric ramifications
por: Qureshi, Naseem A.
Publicado: (2004)

Healthcare Teams: Terminology, Confusion, and Ramifications
por: Martin, Aleysha K, et al.
Publicado: (2022)

Editorial: Structural immunology of molecular innate immunity
por: Lee, Jun Hyuck, et al.
Publicado: (2023)

Regulation of CD4(+) T Cell Signaling and Immunological Synapse by Protein Tyrosine Phosphatases: Molecular Mechanisms in Autoimmunity
por: Castro-Sánchez, Patricia, et al.
Publicado: (2019)

Reproductive Immunology Research: A Tight Interaction between Diverse Scientific and Clinical Disciplines Including Immunology, Obstetrics, Hematology, and Endocrinology
por: Giaglis, Stavros, et al.
Publicado: (2015)

An updated review of the immunological mechanisms of keloid scars
por: Lee, Chih-Chun, et al.
Publicado: (2023)

The changing paradigm of intron retention: regulation, ramifications and recipes
por: Monteuuis, Geoffray, et al.
Publicado: (2019)

Type I Interferons in the Pathogenesis of Tuberculosis: Molecular Drivers and Immunological Consequences
por: Donovan, Meg L., et al.
Publicado: (2017)

Clinical and economic ramifications of switching antipsychotics in the treatment of schizophrenia
por: Faries, Douglas E, et al.
Publicado: (2009)

The Immunological Role of CDK4/6 and Potential Mechanism Exploration in Ovarian Cancer
por: Liu, Chen, et al.
Publicado: (2022)

International Conference on Knot Theory and its Ramifications
por: Collective
Publicado: (1998)

Business Unusual: COVID-19 Ramifications for Arthroplasty
por: Wellman, Samuel, et al.
Publicado: (2020)

The ramifications of COVID-19 on maternal health in Kenya
por: Wangamati, Cynthia Khamala, et al.
Publicado: (2020)

Ecological ramifications of adaptation to size-selective mortality
por: Evangelista, Charlotte, et al.
Publicado: (2021)

Stress loading and Psychopathology in Schizophrenia: Ramification for management
por: singh, Krishna Kumar, et al.
Publicado: (2022)

Left Ventricular Assist Devices and Renal Ramifications
por: Nair, Ajith, et al.
Publicado: (2023)

Editorial: Global excellence in molecular immunology and therapeutics: Africa 2021
por: Ahmad, Tarek A., et al.
Publicado: (2023)

Roles of Carotenoids in Invertebrate Immunology
por: Tan, Karsoon, et al.
Publicado: (2020)

Physiological/pathological ramifications of transcription factors in the unfolded protein response
por: Han, Jaeseok, et al.
Publicado: (2017)

Editorial: Sentinel CLECs at Immunological Decision Nodes
por: Hoober, J. Kenneth, et al.
Publicado: (2020)

A Review of the Immunological Mechanisms Following Mucosal Vaccination of Finfish
por: Munang’andu, Hetron Mweemba, et al.
Publicado: (2015)

Vaccination Against Tuberculosis: Revamping BCG by Molecular Genetics Guided by Immunology
por: Kaufmann, Stefan H. E.
Publicado: (2020)

Immunological Responses to Envenomation
por: Ryan, Rachael Y. M., et al.
Publicado: (2021)

Loss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy
por: Henpita, Chathurika, et al.
Publicado: (2023)

Ramification theoretic methods in algebraic geometry (AM-43)
por: Abhyankar, Shreeram Shankar
Publicado: (1959)

Cannot write session to /tmp/vufind_sessions/sess_flmjhci024q5danromjj9lad9b