Cargando…

Beware of the Potential Risks for Polygoni Multiflori Caulis-Induced Liver Injury

Background: Reynoutria multiflora (Thunb.) Moldenke (PM) is a widely-used medicinal plant in China, whose root and stem are included in the Chinese Pharmacopoeia as Polygoni Multiflori Radix (RPM), Polygoni Multiflori Radix Preparata (PMP), and Polygoni Multiflori Caulis (PMC). The hepatotoxicity of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kong, Wei-Song, Zhou, Gui, Xu, Li-Wei, Wang, Kun, Feng, Yi-Ming, Tao, Li-Yu, Xie, Rui-Fang, Yang, Ming, Zhou, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010879/ https://www.ncbi.nlm.nih.gov/pubmed/35431961 http://dx.doi.org/10.3389/fphar.2022.868327

Ejemplares similares

Poria Attenuates Idiosyncratic Liver Injury Induced by Polygoni Multiflori Radix Praeparata
por: Gao, Dan, et al.
Publicado: (2016)

Hepatotoxic metabolites in Polygoni Multiflori Radix— Comparative toxicology in mice
por: Wang, Shixiao, et al.
Publicado: (2022)

Quality assessment on Polygoni Multiflori Caulis using HPLC/UV/MS combined with principle component analysis
por: Zhao, Yang, et al.
Publicado: (2013)

Integrating Targeted and Untargeted Metabolomics to Investigate the Processing Chemistry of Polygoni Multiflori Radix
por: Liang, Li, et al.
Publicado: (2018)

Pharmacokinetics, Tissue Distribution, and Excretion Characteristics of a Radix Polygoni Multiflori Extract in Rats
por: Cheng, Wenhao, et al.
Publicado: (2022)

Caulis Polygoni Multiflori Accelerates Megakaryopoiesis and Thrombopoiesis via Activating PI3K/Akt and MEK/ERK Signaling Pathways
por: Yang, Xin, et al.
Publicado: (2022)

Influence Factors on the Hepatotoxicity of Polygoni Multiflori Radix
por: Wei, Yun, et al.
Publicado: (2019)

Overview of Pharmacokinetics and Liver Toxicities of Radix Polygoni Multiflori
por: Li, Dan, et al.
Publicado: (2020)

Hepatotoxicity of the Major Anthraquinones Derived From Polygoni Multiflori Radix Based on Bile Acid Homeostasis
por: Kang, Li, et al.
Publicado: (2022)

Polygoni Multiflori Radix interferes with bile acid metabolism homeostasis by inhibiting Fxr transcription, leading to cholestasis
por: Dai, Yihang, et al.
Publicado: (2023)

Metabolomics profiling of Polygoni Multiflori Radix and Polygoni Multiflori Radix Preparata extracts using UPLC-Q/TOF-MS
por: Zhang, Zhaoyan, et al.
Publicado: (2019)

Detection of Emodin Derived Glutathione Adduct in Normal Rats Administered with Large Dosage of Polygoni Multiflori Radix
por: Jiang, Li-Long, et al.
Publicado: (2017)

Combination of Polygoni Multiflori Radix Praeparata and Acori Tatarinowii Rhizoma Alleviates Learning and Memory Impairment in Scopolamine-Treated Mice by Regulating Synaptic-Related Proteins
por: Ning, Funan, et al.
Publicado: (2021)

Polygoni Multiflori Radix Preparat Delays Skin Aging by Inducing Mitophagy
por: Liu, Xiang, et al.
Publicado: (2021)

A Candidate Drug for Nonalcoholic Fatty Liver Disease: A Review of Pharmacological Activities of Polygoni Multiflori Radix
por: Zhou, Mengting, et al.
Publicado: (2020)

Discrimination of Radix Polygoni Multiflori from different geographical areas by UPLC-QTOF/MS combined with chemometrics
por: Tang, Jin-Fa, et al.
Publicado: (2017)

Intestinal Transportations of Main Chemical Compositions of Polygoni Multiflori Radix in Caco-2 Cell Model
por: Yu, Jie, et al.
Publicado: (2014)

Combination with Red ginseng and Polygoni Multiflori ameliorates highfructose diet induced metabolic syndrome
por: Kho, Min Chul, et al.
Publicado: (2016)

Simultaneous Determination of 13 Constituents of Radix Polygoni Multiflori in Rat Plasma and Its Application in a Pharmacokinetic Study
por: Cheng, Wenhao, et al.
Publicado: (2020)

Biomarkers and Mechanism Analysis for Polygoni Multiflori Radix Preparata-Induced Liver Injury by UHPLC-Q-TOF-MS-Based Metabolomics
por: Wang, Liming, et al.
Publicado: (2021)

In Vivo Lipid Regulation Mechanism of Polygoni Multiflori Radix in High-Fat Diet Fed Rats
por: Lin, Pei, et al.
Publicado: (2014)

The Protective Effect of Radix Polygoni Multiflori on Diabetic Encephalopathy via Regulating Myosin Light Chain Kinase Expression
por: He, Yu, et al.
Publicado: (2015)

On-line identification of the chemical constituents of Polygoni Multiflori Radix by UHPLC-Q-ToF MS/MS
por: Wang, Xueting, et al.
Publicado: (2023)

Polygoni Multiflori Radix Praeparata Ethanol Extract Exerts a Protective Effect Against High-Fat Diet Induced Non-Alcoholic Fatty Liver Disease in Mice by Remodeling Intestinal Microbial Structure and Maintaining Metabolic Homeostasis of Bile Acids
por: Dai, Xuyang, et al.
Publicado: (2021)

Tissue-Specific Analysis of Secondary Metabolites Creates a Reliable Morphological Criterion for Quality Grading of Polygoni Multiflori Radix
por: Liang, Li, et al.
Publicado: (2018)

Comparison of raw and processed Radix Polygoni Multiflori (Heshouwu) by high performance liquid chromatography and mass spectrometry
por: Liang, Zhitao, et al.
Publicado: (2010)

Quality evaluation of various commercial specifications of Polygoni Multiflori Radix and its dregs by determination of active compounds
por: Liang, Zhitao, et al.
Publicado: (2012)

Radix Polygoni Multiflori and Its Main Component Emodin Attenuate Non-Alcoholic Fatty Liver Disease in Zebrafish by Regulation of AMPK Signaling Pathway
por: Yu, Linyuan, et al.
Publicado: (2020)

Effects of Lipid Regulation Using Raw and Processed Radix Polygoni Multiflori in Rats Fed a High-Fat Diet
por: Li, Na, et al.
Publicado: (2012)

Lonicerae Japonicae Caulis: a review of its research progress of active metabolites and pharmacological effects
por: Cao, Yu-Xia, et al.
Publicado: (2023)

Identification and Differentiation of Polygonum multiflorum Radix and Polygoni multiflori Radix Preaparata through the Quantitative Analysis of Multicomponents by the Single-Marker Method
por: Luo, Ding-Qiang, et al.
Publicado: (2019)

High-Throughput Identification of Organic Compounds from Polygoni Multiflori Radix Praeparata (Zhiheshouwu) by UHPLC-Q-Exactive Orbitrap-MS
por: Wang, Shaoyun, et al.
Publicado: (2021)

Study on the Hepatoprotection of Schisandra chinensis Caulis Polysaccharides in Nonalcoholic Fatty Liver Disease in Rats Based on Metabolomics
por: Feng, Yanbo, et al.
Publicado: (2021)

Comparative Investigation of Raw and Processed Radix Polygoni Multiflori on the Treatment of Vascular Dementia by Liquid Chromatograph−Mass Spectrometry Based Metabolomic Approach
por: Wu, Fengye, et al.
Publicado: (2022)

Discrimination and Proper Use of Polygoni Multiflori Radix, Cynanchi Wilfordii Radix, and Cynanchi Auriculati Radix in Korea: A Descriptive Review
por: Lee, Beom-Joon, et al.
Publicado: (2015)

2,3,5,4′-Tetrahydroxystilbene-2-O-β-glucoside Isolated from Polygoni Multiflori Ameliorates the Development of Periodontitis
por: Chin, Yu-Tang, et al.
Publicado: (2016)

Polygoni multiflori radix extracts inhibit SARS-CoV-2 pseudovirus entry in HEK293T cells and zebrafish larvae
por: Wang, Xiaoyang, et al.
Publicado: (2022)

Comprehensive analysis of Polygoni Multiflori Radix of different geographical origins using ultra-high-performance liquid chromatography fingerprints and multivariate chemometric methods
por: Sun, Li-Li, et al.
Publicado: (2016)

Comparison of In Vitro Estrogenic Activity of Polygoni multiflori Radix and Cynanchi wilfordii Radix via the Enhancement of ERα/β Expression in MCF7 Cells
por: Akter, Reshmi, et al.
Publicado: (2023)

Hepatotoxicity in Rats Induced by Aqueous Extract of Polygoni Multiflori Radix, Root of Polygonum multiflorum Related to the Activity Inhibition of CYP1A2 or CYP2E1
por: Li, Deng-Ke, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_sfspi0rdgf178o7v8aintuniv3