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Delivery of Basic Fibroblast Growth Factor Through an In Situ Forming Smart Hydrogel Activates Autophagy in Schwann Cells and Improves Facial Nerves Generation via the PAK-1 Signaling Pathway

Although studies have shown that basic fibroblast growth factor (bFGF) can activate autophagy and promote peripheral nerve repair, the role and the molecular mechanism of action of bFGF in the facial nerve are not clear. In this study, a thermosensitive in situ forming poloxamer hydrogel was used as...

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Detalles Bibliográficos
Autores principales: Hu, Binbin, Zhang, Hanbo, Xu, Menglu, Li, Lei, Wu, Man, Zhang, Susu, Liu, Xuejun, Xia, Weidong, Xu, Ke, Xiao, Jian, Zhang, Hongyu, Ni, Liyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011134/
https://www.ncbi.nlm.nih.gov/pubmed/35431972
http://dx.doi.org/10.3389/fphar.2022.778680