Design, synthesis, and evaluation of 8-aminoquinoline-melatonin derivatives as effective multifunctional agents for Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is thought to be a complex, multifactorial syndrome with many related molecular lesions contributing to its pathogenesis. Thus, multi-target-directed ligands are considered an effective way of treating AD. This study sought to evaluate 8-aminoquinoline-melatonin...

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Detalles Bibliográficos
Autores principales: Chen, Ziwei, Yu, Xuefeng, Chen, Lei, Xu, Lexing, Cai, Yu, Hou, Shanshan, Zheng, Miaodan, Liu, Fuhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011219/
https://www.ncbi.nlm.nih.gov/pubmed/35433950
http://dx.doi.org/10.21037/atm-22-730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011219/
https://www.ncbi.nlm.nih.gov/pubmed/35433950
http://dx.doi.org/10.21037/atm-22-730

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