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Metformin reverses tamoxifen resistance through the lncRNA GAS5-medicated mTOR pathway in breast cancer
BACKGROUND: Metformin (Met) has antitumor effects on various cancers, but it is still unclear whether it exerts a reversible effect on endocrine resistance in breast cancer (BC) patients. In the present survey, metformin’s effects on tamoxifen-resistant MCF cells (The cell line was established at th...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
AME Publishing Company
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011257/ https://www.ncbi.nlm.nih.gov/pubmed/35434034 http://dx.doi.org/10.21037/atm-22-795 |