Cargando…
TRPC3 channel gating by lipids requires localization at the ER/PM junctions defined by STIM1
TRPC3, a member of the transient receptor potential (TRP) superfamily of cation channels, is a lipid-regulated, Ca(2+)-permeable channel that mediates essential components of the receptor evoked Ca(2+) signal. The modes and mechanisms by which lipids regulate TRPC3 and other members of the TRPC chan...
Autores principales: | Liu, Haiping, Lin, Wei-Yin, Leibow, Spencer R., Morateck, Alexander J., Ahuja, Malini, Muallem, Shmuel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011324/ https://www.ncbi.nlm.nih.gov/pubmed/35416932 http://dx.doi.org/10.1083/jcb.202107120 |
Ejemplares similares
-
STIM Proteins and Regulation of SOCE in ER-PM Junctions
por: Ahmad, Moaz, et al.
Publicado: (2022) -
Translocation between PI(4,5)P(2)-poor and PI(4,5)P(2)-rich microdomains during store depletion determines STIM1 conformation and Orai1 gating
por: Maléth, Jozsef, et al.
Publicado: (2014) -
SOAR and the polybasic STIM1 domains gate and regulate the Orai channels
por: Yuan, Joseph P., et al.
Publicado: (2009) -
The STIM1 CTID domain determines access of SARAF to SOAR to regulate Orai1 channel function
por: Jha, Archana, et al.
Publicado: (2013) -
STIM1L traps and gates Orai1 channels without remodeling the cortical ER
por: Saüc, Sophie, et al.
Publicado: (2015)