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TRPC3 channel gating by lipids requires localization at the ER/PM junctions defined by STIM1

TRPC3, a member of the transient receptor potential (TRP) superfamily of cation channels, is a lipid-regulated, Ca(2+)-permeable channel that mediates essential components of the receptor evoked Ca(2+) signal. The modes and mechanisms by which lipids regulate TRPC3 and other members of the TRPC chan...

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Detalles Bibliográficos
Autores principales: Liu, Haiping, Lin, Wei-Yin, Leibow, Spencer R., Morateck, Alexander J., Ahuja, Malini, Muallem, Shmuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011324/
https://www.ncbi.nlm.nih.gov/pubmed/35416932
http://dx.doi.org/10.1083/jcb.202107120

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