X-ray irradiation triggers immune response in human T-lymphocytes via store-operated Ca(2+) entry and NFAT activation

Radiation therapy efficiently eliminates cancer cells and reduces tumor growth. To understand collateral agonistic and antagonistic effects of this treatment on the immune system, we examined the impact of x-ray irradiation on human T cells. We find that, in a major population of leukemic Jurkat T c...

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Detalles Bibliográficos
Autores principales: Tandl, Dominique, Sponagel, Tim, Alansary, Dalia, Fuck, Sebastian, Smit, Timo, Hehlgans, Stephanie, Jakob, Burkhard, Fournier, Claudia, Niemeyer, Barbara A., Rödel, Franz, Roth, Bastian, Moroni, Anna, Thiel, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011325/
https://www.ncbi.nlm.nih.gov/pubmed/35416945
http://dx.doi.org/10.1085/jgp.202112865

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