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Antisense oligonucleotide: A promising therapeutic option to beat COVID‐19

The COVID‐19 crisis and the development of the first approved mRNA vaccine have highlighted the power of RNA‐based therapeutic strategies for the development of new medicines. Aside from RNA‐vaccines, antisense oligonucleotides (ASOs) represent a new and very promising class of RNA‐targeted therapy....

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Detalles Bibliográficos
Autores principales: Quemener, Anaïs M., Galibert, Marie‐Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011570/
https://www.ncbi.nlm.nih.gov/pubmed/34842345
http://dx.doi.org/10.1002/wrna.1703
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author Quemener, Anaïs M.
Galibert, Marie‐Dominique
author_facet Quemener, Anaïs M.
Galibert, Marie‐Dominique
author_sort Quemener, Anaïs M.
collection PubMed
description The COVID‐19 crisis and the development of the first approved mRNA vaccine have highlighted the power of RNA‐based therapeutic strategies for the development of new medicines. Aside from RNA‐vaccines, antisense oligonucleotides (ASOs) represent a new and very promising class of RNA‐targeted therapy. Few drugs have already received approval from the Food and Drug Administration. Here, we underscored why and how ASOs hold the potential to change the therapeutic landscape to beat SARS‐CoV‐2 viral infections. This article is categorized under: RNA Interactions with Proteins and Other Molecules > Small Molecule‐RNA Interactions.
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spelling pubmed-90115702022-04-15 Antisense oligonucleotide: A promising therapeutic option to beat COVID‐19 Quemener, Anaïs M. Galibert, Marie‐Dominique Wiley Interdiscip Rev RNA Focus Article The COVID‐19 crisis and the development of the first approved mRNA vaccine have highlighted the power of RNA‐based therapeutic strategies for the development of new medicines. Aside from RNA‐vaccines, antisense oligonucleotides (ASOs) represent a new and very promising class of RNA‐targeted therapy. Few drugs have already received approval from the Food and Drug Administration. Here, we underscored why and how ASOs hold the potential to change the therapeutic landscape to beat SARS‐CoV‐2 viral infections. This article is categorized under: RNA Interactions with Proteins and Other Molecules > Small Molecule‐RNA Interactions. John Wiley & Sons, Inc. 2021-11-28 2022 /pmc/articles/PMC9011570/ /pubmed/34842345 http://dx.doi.org/10.1002/wrna.1703 Text en © 2021 The Authors. WIREs RNA published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Focus Article
Quemener, Anaïs M.
Galibert, Marie‐Dominique
Antisense oligonucleotide: A promising therapeutic option to beat COVID‐19
title Antisense oligonucleotide: A promising therapeutic option to beat COVID‐19
title_full Antisense oligonucleotide: A promising therapeutic option to beat COVID‐19
title_fullStr Antisense oligonucleotide: A promising therapeutic option to beat COVID‐19
title_full_unstemmed Antisense oligonucleotide: A promising therapeutic option to beat COVID‐19
title_short Antisense oligonucleotide: A promising therapeutic option to beat COVID‐19
title_sort antisense oligonucleotide: a promising therapeutic option to beat covid‐19
topic Focus Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011570/
https://www.ncbi.nlm.nih.gov/pubmed/34842345
http://dx.doi.org/10.1002/wrna.1703
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