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Celastrol mitigates staphyloxanthin biosynthesis and biofilm formation in Staphylococcus aureus via targeting key regulators of virulence; in vitro and in vivo approach

BACKGROUND: Staphylococcus aureus is a leading cause of human infections. The spread of antibiotic-resistant staphylococci has driven the search for novel strategies to supersede antibiotics use. Thus, targeting bacterial virulence rather than viability could be a possible alternative. RESULTS: The...

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Detalles Bibliográficos
Autores principales:	Yehia, Fatma Al-zahraa A., Yousef, Nehal, Askoura, Momen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011992/ https://www.ncbi.nlm.nih.gov/pubmed/35421933 http://dx.doi.org/10.1186/s12866-022-02515-z

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