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Bilateral Facial Palsy Without Ocular Muscle Involvement in Myasthenia Gravis: Case Report
Myasthenia gravis (MG) is an autoimmune neuromuscular junction disorder that is more common among women than men. It has two major subtypes, namely, ocular and generalized MG, and while facial weakness is common in generalized MG, facial weakness without the involvement of ocular muscle is exceeding...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012012/ https://www.ncbi.nlm.nih.gov/pubmed/35444878 http://dx.doi.org/10.7759/cureus.23210 |
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author | Umair, Muhammad Faheem, Filzah Malik, Hashir Amin Hassan, Syed Ahmad Ali Iqbal, Athar |
author_facet | Umair, Muhammad Faheem, Filzah Malik, Hashir Amin Hassan, Syed Ahmad Ali Iqbal, Athar |
author_sort | Umair, Muhammad |
collection | PubMed |
description | Myasthenia gravis (MG) is an autoimmune neuromuscular junction disorder that is more common among women than men. It has two major subtypes, namely, ocular and generalized MG, and while facial weakness is common in generalized MG, facial weakness without the involvement of ocular muscle is exceedingly rare. Here, we describe the case of a middle-aged man who presented with bilateral facial palsy but without diplopia or proximal muscle weakness. The patient tested positive for acetylcholine receptor antibodies and exhibited amplitude decrement on repetitive nerve stimulation, which are diagnostic for MG. This report emphasizes the importance of neurodiagnostic and physiological testing in patients presenting with bilateral facial weakness alone. |
format | Online Article Text |
id | pubmed-9012012 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-90120122022-04-19 Bilateral Facial Palsy Without Ocular Muscle Involvement in Myasthenia Gravis: Case Report Umair, Muhammad Faheem, Filzah Malik, Hashir Amin Hassan, Syed Ahmad Ali Iqbal, Athar Cureus Internal Medicine Myasthenia gravis (MG) is an autoimmune neuromuscular junction disorder that is more common among women than men. It has two major subtypes, namely, ocular and generalized MG, and while facial weakness is common in generalized MG, facial weakness without the involvement of ocular muscle is exceedingly rare. Here, we describe the case of a middle-aged man who presented with bilateral facial palsy but without diplopia or proximal muscle weakness. The patient tested positive for acetylcholine receptor antibodies and exhibited amplitude decrement on repetitive nerve stimulation, which are diagnostic for MG. This report emphasizes the importance of neurodiagnostic and physiological testing in patients presenting with bilateral facial weakness alone. Cureus 2022-03-16 /pmc/articles/PMC9012012/ /pubmed/35444878 http://dx.doi.org/10.7759/cureus.23210 Text en Copyright © 2022, Umair et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Umair, Muhammad Faheem, Filzah Malik, Hashir Amin Hassan, Syed Ahmad Ali Iqbal, Athar Bilateral Facial Palsy Without Ocular Muscle Involvement in Myasthenia Gravis: Case Report |
title | Bilateral Facial Palsy Without Ocular Muscle Involvement in Myasthenia Gravis: Case Report |
title_full | Bilateral Facial Palsy Without Ocular Muscle Involvement in Myasthenia Gravis: Case Report |
title_fullStr | Bilateral Facial Palsy Without Ocular Muscle Involvement in Myasthenia Gravis: Case Report |
title_full_unstemmed | Bilateral Facial Palsy Without Ocular Muscle Involvement in Myasthenia Gravis: Case Report |
title_short | Bilateral Facial Palsy Without Ocular Muscle Involvement in Myasthenia Gravis: Case Report |
title_sort | bilateral facial palsy without ocular muscle involvement in myasthenia gravis: case report |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012012/ https://www.ncbi.nlm.nih.gov/pubmed/35444878 http://dx.doi.org/10.7759/cureus.23210 |
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