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Bilateral Facial Palsy Without Ocular Muscle Involvement in Myasthenia Gravis: Case Report

Myasthenia gravis (MG) is an autoimmune neuromuscular junction disorder that is more common among women than men. It has two major subtypes, namely, ocular and generalized MG, and while facial weakness is common in generalized MG, facial weakness without the involvement of ocular muscle is exceeding...

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Autores principales: Umair, Muhammad, Faheem, Filzah, Malik, Hashir Amin, Hassan, Syed Ahmad Ali, Iqbal, Athar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012012/
https://www.ncbi.nlm.nih.gov/pubmed/35444878
http://dx.doi.org/10.7759/cureus.23210
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author Umair, Muhammad
Faheem, Filzah
Malik, Hashir Amin
Hassan, Syed Ahmad Ali
Iqbal, Athar
author_facet Umair, Muhammad
Faheem, Filzah
Malik, Hashir Amin
Hassan, Syed Ahmad Ali
Iqbal, Athar
author_sort Umair, Muhammad
collection PubMed
description Myasthenia gravis (MG) is an autoimmune neuromuscular junction disorder that is more common among women than men. It has two major subtypes, namely, ocular and generalized MG, and while facial weakness is common in generalized MG, facial weakness without the involvement of ocular muscle is exceedingly rare. Here, we describe the case of a middle-aged man who presented with bilateral facial palsy but without diplopia or proximal muscle weakness. The patient tested positive for acetylcholine receptor antibodies and exhibited amplitude decrement on repetitive nerve stimulation, which are diagnostic for MG. This report emphasizes the importance of neurodiagnostic and physiological testing in patients presenting with bilateral facial weakness alone.
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spelling pubmed-90120122022-04-19 Bilateral Facial Palsy Without Ocular Muscle Involvement in Myasthenia Gravis: Case Report Umair, Muhammad Faheem, Filzah Malik, Hashir Amin Hassan, Syed Ahmad Ali Iqbal, Athar Cureus Internal Medicine Myasthenia gravis (MG) is an autoimmune neuromuscular junction disorder that is more common among women than men. It has two major subtypes, namely, ocular and generalized MG, and while facial weakness is common in generalized MG, facial weakness without the involvement of ocular muscle is exceedingly rare. Here, we describe the case of a middle-aged man who presented with bilateral facial palsy but without diplopia or proximal muscle weakness. The patient tested positive for acetylcholine receptor antibodies and exhibited amplitude decrement on repetitive nerve stimulation, which are diagnostic for MG. This report emphasizes the importance of neurodiagnostic and physiological testing in patients presenting with bilateral facial weakness alone. Cureus 2022-03-16 /pmc/articles/PMC9012012/ /pubmed/35444878 http://dx.doi.org/10.7759/cureus.23210 Text en Copyright © 2022, Umair et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Umair, Muhammad
Faheem, Filzah
Malik, Hashir Amin
Hassan, Syed Ahmad Ali
Iqbal, Athar
Bilateral Facial Palsy Without Ocular Muscle Involvement in Myasthenia Gravis: Case Report
title Bilateral Facial Palsy Without Ocular Muscle Involvement in Myasthenia Gravis: Case Report
title_full Bilateral Facial Palsy Without Ocular Muscle Involvement in Myasthenia Gravis: Case Report
title_fullStr Bilateral Facial Palsy Without Ocular Muscle Involvement in Myasthenia Gravis: Case Report
title_full_unstemmed Bilateral Facial Palsy Without Ocular Muscle Involvement in Myasthenia Gravis: Case Report
title_short Bilateral Facial Palsy Without Ocular Muscle Involvement in Myasthenia Gravis: Case Report
title_sort bilateral facial palsy without ocular muscle involvement in myasthenia gravis: case report
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012012/
https://www.ncbi.nlm.nih.gov/pubmed/35444878
http://dx.doi.org/10.7759/cureus.23210
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