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LinDA: linear models for differential abundance analysis of microbiome compositional data
Differential abundance analysis is at the core of statistical analysis of microbiome data. The compositional nature of microbiome sequencing data makes false positive control challenging. Here, we show that the compositional effects can be addressed by a simple, yet highly flexible and scalable, app...
Autores principales: | Zhou, Huijuan, He, Kejun, Chen, Jun, Zhang, Xianyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012043/ https://www.ncbi.nlm.nih.gov/pubmed/35421994 http://dx.doi.org/10.1186/s13059-022-02655-5 |
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