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LinDA: linear models for differential abundance analysis of microbiome compositional data

Differential abundance analysis is at the core of statistical analysis of microbiome data. The compositional nature of microbiome sequencing data makes false positive control challenging. Here, we show that the compositional effects can be addressed by a simple, yet highly flexible and scalable, app...

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Detalles Bibliográficos
Autores principales: Zhou, Huijuan, He, Kejun, Chen, Jun, Zhang, Xianyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012043/
https://www.ncbi.nlm.nih.gov/pubmed/35421994
http://dx.doi.org/10.1186/s13059-022-02655-5

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