PolyMyalgia Rheumatica treatment with Methotrexate in Optimal Dose in an Early disease phase (PMR MODE): study protocol for a multicenter double-blind placebo controlled trial

BACKGROUND: Polymyalgia rheumatica (PMR) is an inflammatory rheumatic disease affecting people older than 50, resulting in pain and stiffness of the neck, shoulder, and pelvic girdle. To date, glucocorticoids (GC) remain the cornerstone of treatment, but these have several drawbacks. Firstly, a larg...

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Detalles Bibliográficos
Autores principales: Marsman, Diane E., Bolhuis, Thomas E., den Broeder, Nathan, den Broeder, Alfons A., van der Maas, Aatke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012047/
https://www.ncbi.nlm.nih.gov/pubmed/35428320
http://dx.doi.org/10.1186/s13063-022-06263-3

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